Conserved basal lamina proteins, laminin and nidogen, are repurposed to organize mechanosensory complexes responsible for touch sensation

Alakananda Das; Joy A. Franco; Ben Mulcahy; Lingxin Wang; Dail Chapman; Chandni Jaisinghani; Beth L. Pruitt; Mei Zhen; Miriam B. Goodman

doi:10.1101/2022.02.11.479800

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doi

https://doi.org/10.1101/2022.02.11.479800

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December 26, 2023.

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Author Information

Alakananda Das1,†,
Joy A. Franco2,†,
Ben Mulcahy4,
Lingxin Wang1,†,
Dail Chapman1,†,
Chandni Jaisinghani1,
Beth L. Pruitt3,
Mei Zhen4 and
Miriam B. Goodman1,*

¹Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305
²Department of Mechanical Engineering, Stanford University, Stanford, CA 94305
³Departments of Mechanical Engineering and Molecular, Cellular, & Developmental Biology, University of California Santa Barbara, Santa Barbara, CA 93106
⁴Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada

↵*Correspondence: mbgoodmn{at}stanford.edu

↵† Alakananda Das, Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125
Joy A. Franco, Department of Neurobiology, Harvard Medical School, Boston, MA 02115
Dail Chapman, Department of Biology, Georgetown University, Washington, DC 20057
Lingxin Wang, Novel Human Genetics Research Unit, GSK, Collegeville, PA 19426