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Brain endothelial STING1 activation by Plasmodium-sequestered heme promotes cerebral malaria via type I IFN response
View ORCID ProfileTeresa F. Pais, Hajrabibi Ali, Joana Moreira da Silva, Nádia Duarte, Rita Neres, View ORCID ProfileChintan Chhatbar, Rita C. Acúrcio, Rita C. Guedes, View ORCID ProfileMaria Carolina Strano Moraes, Bruno Costa Silva, Ulrich Kalinke, Carlos Penha-Gonçalves
doi: https://doi.org/10.1101/2022.02.14.480268
Teresa F. Pais
1Instituto Gulbenkian de Ciência; Oeiras, Portugal
Hajrabibi Ali
1Instituto Gulbenkian de Ciência; Oeiras, Portugal
Joana Moreira da Silva
1Instituto Gulbenkian de Ciência; Oeiras, Portugal
2CIISA, Faculdade de Medicina Veterinária, Universidade de Lisboa; Lisbon, Portugal
Nádia Duarte
1Instituto Gulbenkian de Ciência; Oeiras, Portugal
Rita Neres
1Instituto Gulbenkian de Ciência; Oeiras, Portugal
Chintan Chhatbar
3Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School; Hannover, Germany
4Institute of Neuropathology, Medical Faculty, University of Freiburg; Freiburg, Germany
Rita C. Acúrcio
5Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa; Lisbon, Portugal
Rita C. Guedes
5Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa; Lisbon, Portugal
Maria Carolina Strano Moraes
6Systems Oncology Group, Champalimaud Research, Champalimaud Centre for the Unknown; Lisbon, Portugal
Bruno Costa Silva
6Systems Oncology Group, Champalimaud Research, Champalimaud Centre for the Unknown; Lisbon, Portugal
Ulrich Kalinke
3Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School; Hannover, Germany
Carlos Penha-Gonçalves
1Instituto Gulbenkian de Ciência; Oeiras, Portugal
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Posted April 12, 2022.
Brain endothelial STING1 activation by Plasmodium-sequestered heme promotes cerebral malaria via type I IFN response
Teresa F. Pais, Hajrabibi Ali, Joana Moreira da Silva, Nádia Duarte, Rita Neres, Chintan Chhatbar, Rita C. Acúrcio, Rita C. Guedes, Maria Carolina Strano Moraes, Bruno Costa Silva, Ulrich Kalinke, Carlos Penha-Gonçalves
bioRxiv 2022.02.14.480268; doi: https://doi.org/10.1101/2022.02.14.480268
Brain endothelial STING1 activation by Plasmodium-sequestered heme promotes cerebral malaria via type I IFN response
Teresa F. Pais, Hajrabibi Ali, Joana Moreira da Silva, Nádia Duarte, Rita Neres, Chintan Chhatbar, Rita C. Acúrcio, Rita C. Guedes, Maria Carolina Strano Moraes, Bruno Costa Silva, Ulrich Kalinke, Carlos Penha-Gonçalves
bioRxiv 2022.02.14.480268; doi: https://doi.org/10.1101/2022.02.14.480268
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