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History
- February 28, 2022.
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Author Information
- Fan Zhang1,2,3,4,5,6,28,
- Anna Helena Jonsson1,28,
- Aparna Nathan1,2,3,4,5,28,
- Kevin Wei1,28,
- Nghia Millard1,2,3,4,5,28,
- Qian Xiao1,2,3,4,5,
- Maria Gutierrez-Arcelus1,2,3,4,5,7,
- William Apruzzese8,
- Gerald F. M. Watts1,
- Dana Weisenfeld1,
- Joyce B. Kang1,2,3,4,5,
- Laurie Rumker1,2,3,4,5,
- Joseph Mears1,2,3,4,5,
- Kamil Slowikowski4,5,9,10,
- Kathryn Weinand1,2,3,4,5,
- Dana E. Orange11,12,
- Javier Rangel-Moreno13,
- Laura Geraldino-Pardilla14,
- Kevin D. Deane15,
- Darren Tabechian13,
- Arnold Ceponis16,
- Gary S. Firestein16,
- Mark Maybury17,
- Ilfita Sahbudin17,
- Ami Ben-Artzi18,
- Arthur M. Mandelin II19,
- Alessandra Nerviani20,
- Felice Rivellese20,
- Costantino Pitzalis20,
- Laura B. Hughes21,
- Diane Horowitz22,
- Edward DiCarlo23,
- Ellen M. Gravallese1,
- Brendan F. Boyce24,
- Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network,
- Larry W. Moreland15,25,
- Susan M. Goodman11,26,
- Harris Perlman19,
- V. Michael Holers15,
- Katherine P. Liao1,4,
- Andrew Filer17,
- Vivian P. Bykerk11,26,
- Deepak A. Rao1,*,
- Laura T. Donlin11,26,*,
- Jennifer H. Anolik13,*,
- Michael B. Brenner1,*,
- Soumya Raychaudhuri1,2,3,4,5,27,*,†,
- Jennifer Albrecht13,
- Jennifer L. Barnas13,
- Joan M. Bathon14,
- David L. Boyle16,
- S. Louis Bridges Jr.11,26,
- Debbie Campbell13,
- Hayley L. Carr17,
- Adam Chicoine1,
- Andrew Cordle29,
- Michelle Curtis1,2,3,4,5,
- Patrick Dunn30,31,
- Lindsy Forbess17,
- Peter K. Gregersen22,
- Joel M. Guthridge32,
- Lionel B. Ivashkiv11,26,
- Kazuyoshi Ishigaki1,2,3,4,5,33,
- Judith A. James32,
- Gregory Keras1,
- Ilya Korsunsky1,2,3,4,5,
- Amit Lakhanpal11,26,
- James A. Lederer34,
- Zhihan J. Li1,
- Yuhong Li1,
- Andrew McDavid35,
- Nida Meednu13,
- Ian Mantel11,26,
- Mandy J. McGeachy25,
- Karim Raza17,
- Yakir Reshef1,2,3,4,5,
- Christopher Ritchlin13,
- William H. Robinson36,
- Saori Sakaue1,2,3,4,5,
- Jennifer A. Seifert15,
- Melanie H. Smith11,
- Dagmar Scheel-Toellner17,
- Paul J. Utz36,
- Michael H. Weisman18,36 and
- Zhu Zhu1
- 1Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA
- 2Center for Data Sciences, Brigham and Women’s Hospital, Boston, MA, USA
- 3Division of Genetics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA
- 4Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
- 5Broad Institute of MIT and Harvard, Cambridge, MA, USA
- 6Division of Rheumatology and the Center for Health Artificial Intelligence, University of Colorado School of Medicine, Aurora, CO, USA
- 7Division of Immunology, Department of Pediatrics, Boston Children’s Hospital and Harvard Medical School, Boston, MA. US
- 8Accelerating Medicines Partnership® Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP® RA/SLE) Network
- 9Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital (MGH), Boston, MA, USA
- 10MGH Cancer Center, Boston, MA, USA
- 11Hospital for Special Surgery, New York, NY, USA
- 12Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, NY, USA
- 13Division of Allergy, Immunology and Rheumatology; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA
- 14Division of Rheumatology, Columbia University College of Physicians and Surgeons, New York, NY, USA
- 15Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, USA
- 16Division of Rheumatology, Allergy and Immunology, University of California, San Diego, La Jolla, CA, USA
- 17Rheumatology Research Group, Institute for Inflammation and Ageing, University of Birmingham, NIHR Birmingham Biomedical Research Center and Clinical Research Facility, University of Birmingham, Queen Elizabeth Hospital, Birmingham, UK
- 18Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA
- 19Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
- 20Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Queen Mary University of London; London, UK
- 21Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
- 22Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, NY, USA
- 23Department of Pathology and Laboratory Medicine, Hospital for Special Surgery; New York, NY, USA
- 24Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA
- 25Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA
- 26Weill Cornell Medicine, New York, NY, USA
- 27Versus Arthritis Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
- 29Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
- 30Division of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
- 31Northrop Grumman Health Solutions, Rockville, MD, USA
- 32Department of Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation; Oklahoma City, OK, USA
- 33Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
- 34Department of Surgery, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA
- 35Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry; Rochester, NY, USA
- 36Division of Immunology and Rheumatology, Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA
- ↵†Corresponding author; email: soumya{at}broadinstitute.org
↵28 These authors contributed equally