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Multi-omic analysis along the gut-brain axis points to a functional architecture of autism
View ORCID ProfileJames T. Morton, View ORCID ProfileDong-Min Jin, View ORCID ProfileRobert H. Mills, View ORCID ProfileYan Shao, View ORCID ProfileGibraan Rahman, View ORCID ProfileDaniel McDonald, View ORCID ProfileKirsten Berding, View ORCID ProfileBrittany D. Needham, View ORCID ProfileMaría Fernanda Zurita, View ORCID ProfileMaude David, View ORCID ProfileOlga V. Averina, View ORCID ProfileAlexey S. Kovtun, View ORCID ProfileAntonio Noto, View ORCID ProfileMichele Mussap, View ORCID ProfileMingbang Wang, View ORCID ProfileDaniel N. Frank, View ORCID ProfileEllen Li, View ORCID ProfileWenhao Zhou, View ORCID ProfileVassilios Fanos, View ORCID ProfileValery N. Danilenko, View ORCID ProfileDennis P. Wall, View ORCID ProfilePaúl Cárdenas, View ORCID ProfileManuel E. Baldeón, View ORCID ProfileRamnik J. Xavier, View ORCID ProfileSarkis K. Mazmanian, View ORCID ProfileRob Knight, View ORCID ProfileJack A. Gilbert, View ORCID ProfileSharon M. Donovan, View ORCID ProfileTrevor D. Lawley, View ORCID ProfileBob Carpenter, View ORCID ProfileRichard Bonneau, View ORCID ProfileGaspar Taroncher-Oldenburg
doi: https://doi.org/10.1101/2022.02.25.482050
James T. Morton
1Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY, USA
2The Simons Foundation Autism Research Initiative, Simons Foundation, New York, NY, USA
Dong-Min Jin
3Center for Genomics and Systems Biology, Department of Biology, New York University, New York, NY, USA
Robert H. Mills
4Precidiag Inc, Watertown, MA, USA
Yan Shao
5Host-Microbiota Interactions Laboratory, Wellcome Sanger Institute, Hinxton, UK
Gibraan Rahman
6Bioinformatics and Systems Biology Program, University of California San Diego, San Diego, CA, USA
7Department of Pediatrics, School of Medicine, University of California San Diego, San Diego, CA, USA
Daniel McDonald
7Department of Pediatrics, School of Medicine, University of California San Diego, San Diego, CA, USA
Kirsten Berding
8Division of Nutritional Sciences, University of Illinois, Urbana, IL, USA
Brittany D. Needham
9Division of Biology & Biological Engineering, California Institute of Technology, Pasadena, CA, USA
María Fernanda Zurita
10Microbiology Institute and Health Science College, Universidad San Francisco de Quito, Quito, Ecuador
Maude David
11Departments of Microbiology & Pharmaceutical Sciences, Oregon State University, Corvallis, OR, USA
Olga V. Averina
12Vavilov Institute of General Genetics Russian Academy of Sciences, Moscow, Russia
Alexey S. Kovtun
12Vavilov Institute of General Genetics Russian Academy of Sciences, Moscow, Russia
13Skolkovo Institute of Science and Technology, Skolkovo, Russia
Antonio Noto
14Department of Biomedical Sciences, School of Medicine, University of Cagliari, Cagliari, Italy
Michele Mussap
15Laboratory Medicine, Department of Surgical Sciences, School of Medicine, University of Cagliari, Italy
Mingbang Wang
16Children’s Hospital of Fudan University, National Center for Children’s Health, Shanghai, China
Daniel N. Frank
17Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA
Ellen Li
18Department of Medicine, Division of Gastroenterology and Hepatology, Stony Brook University, Stony Brook, NY, USA
Wenhao Zhou
16Children’s Hospital of Fudan University, National Center for Children’s Health, Shanghai, China
Vassilios Fanos
19Neonatal Intensive Care Unit and Neonatal Pathology, Department of Surgical Sciences, School of Medicine, University of Cagliari, Italy
Valery N. Danilenko
12Vavilov Institute of General Genetics Russian Academy of Sciences, Moscow, Russia
Dennis P. Wall
20Pediatrics (Systems Medicine), Biomedical Data Science, and Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
Paúl Cárdenas
21Institute of Microbiology, COCIBA, Universidad San Francisco de Quito, Quito, Ecuador
Manuel E. Baldeón
22Facultad de Ciencias Médicas, de la Salud y la Vida, Universidad Internacional del Ecuador, Quito, Ecuador
Ramnik J. Xavier
23Broad Institute of MIT and Harvard, Cambridge, MA, USA
24Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA
25Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA, USA
Sarkis K. Mazmanian
9Division of Biology & Biological Engineering, California Institute of Technology, Pasadena, CA, USA
Rob Knight
7Department of Pediatrics, School of Medicine, University of California San Diego, San Diego, CA, USA
26Department of Computer Science and Engineering, University of California, San Diego, La Jolla, California, USA
27Department of Bioengineering, University of California San Diego, La Jolla, California, USA
Jack A. Gilbert
7Department of Pediatrics, School of Medicine, University of California San Diego, San Diego, CA, USA
28Scripps Institution of Oceanography, UC San Diego, La Jolla, CA, USA
Sharon M. Donovan
8Division of Nutritional Sciences, University of Illinois, Urbana, IL, USA
Trevor D. Lawley
5Host-Microbiota Interactions Laboratory, Wellcome Sanger Institute, Hinxton, UK
Bob Carpenter
1Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY, USA
Richard Bonneau
1Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY, USA
3Center for Genomics and Systems Biology, Department of Biology, New York University, New York, NY, USA
29Prescient Design, a Genentech Accelerator, New York, NY, USA
Gaspar Taroncher-Oldenburg
2The Simons Foundation Autism Research Initiative, Simons Foundation, New York, NY, USA
Article usage
Posted March 09, 2022.
Multi-omic analysis along the gut-brain axis points to a functional architecture of autism
James T. Morton, Dong-Min Jin, Robert H. Mills, Yan Shao, Gibraan Rahman, Daniel McDonald, Kirsten Berding, Brittany D. Needham, María Fernanda Zurita, Maude David, Olga V. Averina, Alexey S. Kovtun, Antonio Noto, Michele Mussap, Mingbang Wang, Daniel N. Frank, Ellen Li, Wenhao Zhou, Vassilios Fanos, Valery N. Danilenko, Dennis P. Wall, Paúl Cárdenas, Manuel E. Baldeón, Ramnik J. Xavier, Sarkis K. Mazmanian, Rob Knight, Jack A. Gilbert, Sharon M. Donovan, Trevor D. Lawley, Bob Carpenter, Richard Bonneau, Gaspar Taroncher-Oldenburg
bioRxiv 2022.02.25.482050; doi: https://doi.org/10.1101/2022.02.25.482050
Multi-omic analysis along the gut-brain axis points to a functional architecture of autism
James T. Morton, Dong-Min Jin, Robert H. Mills, Yan Shao, Gibraan Rahman, Daniel McDonald, Kirsten Berding, Brittany D. Needham, María Fernanda Zurita, Maude David, Olga V. Averina, Alexey S. Kovtun, Antonio Noto, Michele Mussap, Mingbang Wang, Daniel N. Frank, Ellen Li, Wenhao Zhou, Vassilios Fanos, Valery N. Danilenko, Dennis P. Wall, Paúl Cárdenas, Manuel E. Baldeón, Ramnik J. Xavier, Sarkis K. Mazmanian, Rob Knight, Jack A. Gilbert, Sharon M. Donovan, Trevor D. Lawley, Bob Carpenter, Richard Bonneau, Gaspar Taroncher-Oldenburg
bioRxiv 2022.02.25.482050; doi: https://doi.org/10.1101/2022.02.25.482050
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