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RK-33, a small molecule inhibitor of host RNA helicase DDX3, suppresses multiple variants of SARS-CoV-2
Farhad Vesuna, Ivan Akhrymuk, Amy Smith, Paul T. Winnard Jr., Shih-Chao Lin, Robert Scharpf, Kylene Kehn-Hall, Venu Raman
doi: https://doi.org/10.1101/2022.02.28.482334
Farhad Vesuna
1Division of Cancer Imaging Research, Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD
Ivan Akhrymuk
2Department of Biomedical Science and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA
Amy Smith
2Department of Biomedical Science and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA
Paul T. Winnard Jr.
1Division of Cancer Imaging Research, Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD
Shih-Chao Lin
3Bachelor Degree Program in Marine Biotechnology, College of Life Sciences, National Taiwan Ocean University, Keelung, Taiwan
Robert Scharpf
4Division of Biostatistics and Bioinformatics, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD
Kylene Kehn-Hall
2Department of Biomedical Science and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA
5Center for Zoonotic and Arthropod-borne Pathogens, Virginia Polytechnic Institute and State University, Blacksburg, VA
Venu Raman
6Division of Cancer Imaging Research, Department of Radiology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD
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Posted March 01, 2022.
RK-33, a small molecule inhibitor of host RNA helicase DDX3, suppresses multiple variants of SARS-CoV-2
Farhad Vesuna, Ivan Akhrymuk, Amy Smith, Paul T. Winnard Jr., Shih-Chao Lin, Robert Scharpf, Kylene Kehn-Hall, Venu Raman
bioRxiv 2022.02.28.482334; doi: https://doi.org/10.1101/2022.02.28.482334
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