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Gene Expression and Tracer-Based Metabolic Flux Analysis Reveals Tissue-Specific Metabolic Scaling in vitro, ex vivo, and in vivo

View ORCID ProfileNgozi D. Akingbesote, View ORCID ProfileBrooks P. Leitner, View ORCID ProfileDaniel G. Jovin, View ORCID ProfileReina Desrouleaux, Wanling Zhu, View ORCID ProfileZongyu Li, View ORCID ProfileMichael N. Pollak, View ORCID ProfileRachel J. Perry
doi: https://doi.org/10.1101/2022.03.02.482685
Ngozi D. Akingbesote
1Departments of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06510
2Departments of Internal Medicine – Endocrinology, Yale School of Medicine, New Haven, CT 06510
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  • ORCID record for Ngozi D. Akingbesote
Brooks P. Leitner
1Departments of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06510
2Departments of Internal Medicine – Endocrinology, Yale School of Medicine, New Haven, CT 06510
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Daniel G. Jovin
1Departments of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06510
2Departments of Internal Medicine – Endocrinology, Yale School of Medicine, New Haven, CT 06510
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Reina Desrouleaux
1Departments of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06510
3Departments of Comparative Medicine, Yale School of Medicine, New Haven, CT 06510
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Wanling Zhu
1Departments of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06510
2Departments of Internal Medicine – Endocrinology, Yale School of Medicine, New Haven, CT 06510
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Zongyu Li
1Departments of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06510
2Departments of Internal Medicine – Endocrinology, Yale School of Medicine, New Haven, CT 06510
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Michael N. Pollak
4Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada
5Department of Oncology, McGill University, Montreal, QC, Canada
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Rachel J. Perry
1Departments of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06510
2Departments of Internal Medicine – Endocrinology, Yale School of Medicine, New Haven, CT 06510
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  • For correspondence: rachel.perry@yale.edu
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Article Information

doi 
https://doi.org/10.1101/2022.03.02.482685
History 
  • March 4, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Ngozi D. Akingbesote1,2,*,
  2. Brooks P. Leitner1,2,*,
  3. Daniel G. Jovin1,2,
  4. Reina Desrouleaux1,3,
  5. Wanling Zhu1,2,
  6. Zongyu Li1,2,
  7. Michael N. Pollak4,5 and
  8. Rachel J. Perry1,2,+
  1. 1Departments of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06510
  2. 2Departments of Internal Medicine – Endocrinology, Yale School of Medicine, New Haven, CT 06510
  3. 3Departments of Comparative Medicine, Yale School of Medicine, New Haven, CT 06510
  4. 4Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada
  5. 5Department of Oncology, McGill University, Montreal, QC, Canada
  1. ↵+To whom correspondence should be addressed: rachel.perry{at}yale.edu
  1. ↵* Equal contributions

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Posted March 04, 2022.
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Gene Expression and Tracer-Based Metabolic Flux Analysis Reveals Tissue-Specific Metabolic Scaling in vitro, ex vivo, and in vivo
Ngozi D. Akingbesote, Brooks P. Leitner, Daniel G. Jovin, Reina Desrouleaux, Wanling Zhu, Zongyu Li, Michael N. Pollak, Rachel J. Perry
bioRxiv 2022.03.02.482685; doi: https://doi.org/10.1101/2022.03.02.482685
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Gene Expression and Tracer-Based Metabolic Flux Analysis Reveals Tissue-Specific Metabolic Scaling in vitro, ex vivo, and in vivo
Ngozi D. Akingbesote, Brooks P. Leitner, Daniel G. Jovin, Reina Desrouleaux, Wanling Zhu, Zongyu Li, Michael N. Pollak, Rachel J. Perry
bioRxiv 2022.03.02.482685; doi: https://doi.org/10.1101/2022.03.02.482685

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