New Results
Automated patch clamp screening of amiloride and 5-N,N-hexamethyleneamiloride (HMA) analogs identifies 6-iodoamiloride as a potent acid-sensing ion channel inhibitor
View ORCID ProfileRocio K. Finol-Urdaneta, View ORCID ProfileJeffrey R. McArthur, Ashraf Aboelela, View ORCID ProfileRichard S. Bujaroski, View ORCID ProfileHiwa Majed, View ORCID ProfileAlejandra Rangel, View ORCID ProfileDavid J. Adams, View ORCID ProfileMarie Ranson, View ORCID ProfileMichael J. Kelso, View ORCID ProfileBenjamin J. Buckley
doi: https://doi.org/10.1101/2022.03.12.484055
Rocio K. Finol-Urdaneta
aElectrophysiology Facility for Cell Phenotyping and Drug Discovery, Wollongong, NSW 2522, Australia
bIllawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia
Jeffrey R. McArthur
bIllawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia
Ashraf Aboelela
cSchool of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia
Richard S. Bujaroski
bIllawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia
cSchool of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia
Hiwa Majed
cSchool of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia
Alejandra Rangel
bIllawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia
David J. Adams
bIllawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia
dMolecular Horizons, University of Wollongong, NSW 2522, Australia
Marie Ranson
bIllawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia
cSchool of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia
Michael J. Kelso
bIllawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia
cSchool of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia
Benjamin J. Buckley
bIllawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia
cSchool of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia
dMolecular Horizons, University of Wollongong, NSW 2522, Australia
Article usage
Posted March 14, 2022.
Automated patch clamp screening of amiloride and 5-N,N-hexamethyleneamiloride (HMA) analogs identifies 6-iodoamiloride as a potent acid-sensing ion channel inhibitor
Rocio K. Finol-Urdaneta, Jeffrey R. McArthur, Ashraf Aboelela, Richard S. Bujaroski, Hiwa Majed, Alejandra Rangel, David J. Adams, Marie Ranson, Michael J. Kelso, Benjamin J. Buckley
bioRxiv 2022.03.12.484055; doi: https://doi.org/10.1101/2022.03.12.484055
Automated patch clamp screening of amiloride and 5-N,N-hexamethyleneamiloride (HMA) analogs identifies 6-iodoamiloride as a potent acid-sensing ion channel inhibitor
Rocio K. Finol-Urdaneta, Jeffrey R. McArthur, Ashraf Aboelela, Richard S. Bujaroski, Hiwa Majed, Alejandra Rangel, David J. Adams, Marie Ranson, Michael J. Kelso, Benjamin J. Buckley
bioRxiv 2022.03.12.484055; doi: https://doi.org/10.1101/2022.03.12.484055
Subject Area
Subject Areas
- Biochemistry (11736)
- Bioengineering (8749)
- Bioinformatics (29186)
- Biophysics (14964)
- Cancer Biology (12086)
- Cell Biology (17403)
- Clinical Trials (138)
- Developmental Biology (9418)
- Ecology (14176)
- Epidemiology (2067)
- Evolutionary Biology (18299)
- Genetics (12235)
- Genomics (16795)
- Immunology (11863)
- Microbiology (28066)
- Molecular Biology (11582)
- Neuroscience (60936)
- Paleontology (451)
- Pathology (1870)
- Pharmacology and Toxicology (3238)
- Physiology (4956)
- Plant Biology (10423)
- Synthetic Biology (2883)
- Systems Biology (7338)
- Zoology (1650)