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Novel Methods for Multi-ancestry Polygenic Prediction and their Evaluations in 3.7 Million Individuals of Diverse Ancestry
View ORCID ProfileHaoyu Zhang, Jianan Zhan, Jin Jin, Jingning Zhang, Thomas U. Ahearn, Zhi Yu, Jared O’Connell, Yunxuan Jiang, Tony Chen, 23andMe Research Team, View ORCID ProfileMontserrat Garcia-Closas, Xihong Lin, Bertram L. Koelsch, Nilanjan Chatterjee
doi: https://doi.org/10.1101/2022.03.24.485519
Haoyu Zhang
1Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA
4Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Jianan Zhan
223andMe Inc., Sunnyvale, CA, USA
Jin Jin
3Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Jingning Zhang
3Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Thomas U. Ahearn
4Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Zhi Yu
5Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Jared O’Connell
223andMe Inc., Sunnyvale, CA, USA
Yunxuan Jiang
223andMe Inc., Sunnyvale, CA, USA
Tony Chen
1Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA
Montserrat Garcia-Closas
4Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Xihong Lin
1Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA
5Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA
6Department of Statistics, Harvard University, Cambridge, MA, USA
Bertram L. Koelsch
223andMe Inc., Sunnyvale, CA, USA
Nilanjan Chatterjee
3Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
7Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
Posted April 01, 2022.
Novel Methods for Multi-ancestry Polygenic Prediction and their Evaluations in 3.7 Million Individuals of Diverse Ancestry
Haoyu Zhang, Jianan Zhan, Jin Jin, Jingning Zhang, Thomas U. Ahearn, Zhi Yu, Jared O’Connell, Yunxuan Jiang, Tony Chen, 23andMe Research Team, Montserrat Garcia-Closas, Xihong Lin, Bertram L. Koelsch, Nilanjan Chatterjee
bioRxiv 2022.03.24.485519; doi: https://doi.org/10.1101/2022.03.24.485519
Novel Methods for Multi-ancestry Polygenic Prediction and their Evaluations in 3.7 Million Individuals of Diverse Ancestry
Haoyu Zhang, Jianan Zhan, Jin Jin, Jingning Zhang, Thomas U. Ahearn, Zhi Yu, Jared O’Connell, Yunxuan Jiang, Tony Chen, 23andMe Research Team, Montserrat Garcia-Closas, Xihong Lin, Bertram L. Koelsch, Nilanjan Chatterjee
bioRxiv 2022.03.24.485519; doi: https://doi.org/10.1101/2022.03.24.485519
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