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Single-cell transcriptomic atlas of the human substantia nigra in Parkinson’s disease
Qian Wang, Minghui Wang, Insup Choi, Lap Ho, Kurt Farrell, Kristin G. Beaumont, Robert Sebra, John F Crary, David A. Davis, Xiaoyan Sun, Bin Zhang, Zhenyu Yue
doi: https://doi.org/10.1101/2022.03.25.485846
Qian Wang
1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA
2Department of Neurology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA
3Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
4Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
5Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
6Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA.
Minghui Wang
1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA
5Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
6Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA.
Insup Choi
2Department of Neurology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA
3Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
4Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
Lap Ho
1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA
5Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
6Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA.
Kurt Farrell
3Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
4Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
7Department of Pathology, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY, 10029, USA
Kristin G. Beaumont
1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA
Robert Sebra
1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA
6Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA.
8Sema4, a Mount Sinai venture, Stamford, CT 06902, USA
John F Crary
3Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
4Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
7Department of Pathology, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY, 10029, USA
9Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
10Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
David A. Davis
11Department of Neurology, Evelyn F. McKnight Brain Institute, Brain Endowment Bank, University of Miami Miller School of Medicine, FL 33136, USA
Xiaoyan Sun
11Department of Neurology, Evelyn F. McKnight Brain Institute, Brain Endowment Bank, University of Miami Miller School of Medicine, FL 33136, USA
Bin Zhang
1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA
5Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
6Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA.
12Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA
Zhenyu Yue
2Department of Neurology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, NY 10029, USA
3Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
4Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, NY 10029, USA
Article usage
Posted March 30, 2022.
Single-cell transcriptomic atlas of the human substantia nigra in Parkinson’s disease
Qian Wang, Minghui Wang, Insup Choi, Lap Ho, Kurt Farrell, Kristin G. Beaumont, Robert Sebra, John F Crary, David A. Davis, Xiaoyan Sun, Bin Zhang, Zhenyu Yue
bioRxiv 2022.03.25.485846; doi: https://doi.org/10.1101/2022.03.25.485846
Single-cell transcriptomic atlas of the human substantia nigra in Parkinson’s disease
Qian Wang, Minghui Wang, Insup Choi, Lap Ho, Kurt Farrell, Kristin G. Beaumont, Robert Sebra, John F Crary, David A. Davis, Xiaoyan Sun, Bin Zhang, Zhenyu Yue
bioRxiv 2022.03.25.485846; doi: https://doi.org/10.1101/2022.03.25.485846
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