Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures

Daniel Osorio; Parastoo Shahrouzi; Xavier Tekpli; Vessela N. Kristensen; Marieke L. Kuijjer

doi:10.1101/2022.03.31.486602

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Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures

View ORCID ProfileDaniel Osorio, Parastoo Shahrouzi, Xavier Tekpli, Vessela N. Kristensen, View ORCID ProfileMarieke L. Kuijjer

doi: https://doi.org/10.1101/2022.03.31.486602

Daniel Osorio

1Centre for Molecular Medicine Norway (NCMM), University of Oslo, Oslo, Norway

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ORCID record for Daniel Osorio
For correspondence: daniecos@uio.no marieke.kuijjer@ncmm.uio.no

Parastoo Shahrouzi

2Department of Medical Genetics, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway

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Xavier Tekpli

2Department of Medical Genetics, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway

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Vessela N. Kristensen

2Department of Medical Genetics, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway

3Department of Clinical Molecular Biology and Laboratory Science (EpiGen), Division of Medicine, Akershus University Hospital, Lørenskog, Norway

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Marieke L. Kuijjer

1Centre for Molecular Medicine Norway (NCMM), University of Oslo, Oslo, Norway

4Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands

5Leiden Center for Computational Oncology, Leiden University Medical Center (LUMC), Leiden, The Netherlands

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For correspondence: daniecos@uio.no marieke.kuijjer@ncmm.uio.no

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Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures

Daniel Osorio, Parastoo Shahrouzi, Xavier Tekpli, Vessela N. Kristensen, Marieke L. Kuijjer

bioRxiv 2022.03.31.486602; doi: https://doi.org/10.1101/2022.03.31.486602

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Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures

Daniel Osorio, Parastoo Shahrouzi, Xavier Tekpli, Vessela N. Kristensen, Marieke L. Kuijjer

bioRxiv 2022.03.31.486602; doi: https://doi.org/10.1101/2022.03.31.486602

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