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Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation

View ORCID ProfileCourtney J. Smith, View ORCID ProfileNasa Sinnott-Armstrong, View ORCID ProfileAnna Cichońska, View ORCID ProfileHeli Julkunen, View ORCID ProfileEric Fauman, View ORCID ProfilePeter Würtz, View ORCID ProfileJonathan K. Pritchard
doi: https://doi.org/10.1101/2022.04.02.486791
Courtney J. Smith
1Department of Genetics, Stanford University School of Medicine, United States
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  • For correspondence: courtrun@stanford.edu nasa@fredhutch.org pritch@stanford.edu
Nasa Sinnott-Armstrong
1Department of Genetics, Stanford University School of Medicine, United States
2Herbold Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, Washington
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  • For correspondence: courtrun@stanford.edu nasa@fredhutch.org pritch@stanford.edu
Anna Cichońska
3Nightingale Health Plc, Helsinki, Finland
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Heli Julkunen
3Nightingale Health Plc, Helsinki, Finland
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Eric Fauman
4Internal Medicine Research Unit, Pfizer Worldwide Research, Development and Medical, United States
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Peter Würtz
3Nightingale Health Plc, Helsinki, Finland
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Jonathan K. Pritchard
1Department of Genetics, Stanford University School of Medicine, United States
5Department of Biology, Stanford University, United States Joint First Authors
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  • For correspondence: courtrun@stanford.edu nasa@fredhutch.org pritch@stanford.edu
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Posted April 04, 2022.
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Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation
Courtney J. Smith, Nasa Sinnott-Armstrong, Anna Cichońska, Heli Julkunen, Eric Fauman, Peter Würtz, Jonathan K. Pritchard
bioRxiv 2022.04.02.486791; doi: https://doi.org/10.1101/2022.04.02.486791
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Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation
Courtney J. Smith, Nasa Sinnott-Armstrong, Anna Cichońska, Heli Julkunen, Eric Fauman, Peter Würtz, Jonathan K. Pritchard
bioRxiv 2022.04.02.486791; doi: https://doi.org/10.1101/2022.04.02.486791

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