Computational design and construction of an Escherichia coli strain engineered to produce a non-standard amino acid

Ali R. Zomorrodi; Colin Hemez; Pol Arranz-Gibert; Terrence Wu; Farren J. Isaacs; Daniel Segrè

doi:10.1101/2022.04.02.486821

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Computational design and construction of an Escherichia coli strain engineered to produce a non-standard amino acid

Ali R. Zomorrodi, Colin Hemez, Pol Arranz-Gibert, Terrence Wu, Farren J. Isaacs, View ORCID ProfileDaniel Segrè

doi: https://doi.org/10.1101/2022.04.02.486821

Ali R. Zomorrodi

1Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, MA

2Harvard Medical School, Boston, MA

3Bioinformatics Graduate Program, Boston University, Boston, MA

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Colin Hemez

4Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT

5Systems Biology Institute, Yale University, West Haven, CT

6Department of Biomedical Engineering, Yale University, New Haven, CT

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Pol Arranz-Gibert

4Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT

5Systems Biology Institute, Yale University, West Haven, CT

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Terrence Wu

7Yale West Campus Analytical Core, 600 West Campus Drive, West Haven

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Farren J. Isaacs

4Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT

5Systems Biology Institute, Yale University, West Haven, CT

6Department of Biomedical Engineering, Yale University, New Haven, CT

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For correspondence: dsegre@bu.edu farren.isaacs@yale.edu

Daniel Segrè

3Bioinformatics Graduate Program, Boston University, Boston, MA

8Department of Biology, Boston University, Boston, MA

9Department of Biomedical Engineering, Boston University, Boston, MA

10Biological Design Center, Boston University, Boston, MA

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ORCID record for Daniel Segrè
For correspondence: dsegre@bu.edu farren.isaacs@yale.edu

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Supplementary Figures S1 to S5[supplements/486821_file02.pdf]
Supplementary Tables S1 and S2[supplements/486821_file03.pdf]
Supplementary Software S2[supplements/486821_file04.zip]

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Posted April 02, 2022.

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Computational design and construction of an Escherichia coli strain engineered to produce a non-standard amino acid

Ali R. Zomorrodi, Colin Hemez, Pol Arranz-Gibert, Terrence Wu, Farren J. Isaacs, Daniel Segrè

bioRxiv 2022.04.02.486821; doi: https://doi.org/10.1101/2022.04.02.486821

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Computational design and construction of an Escherichia coli strain engineered to produce a non-standard amino acid

Ali R. Zomorrodi, Colin Hemez, Pol Arranz-Gibert, Terrence Wu, Farren J. Isaacs, Daniel Segrè

bioRxiv 2022.04.02.486821; doi: https://doi.org/10.1101/2022.04.02.486821

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