Rational design by structural biology of industrializable, long-acting antihyperglycemic GLP-1 receptor agonists

Lei Sun; Zhi-Ming Zheng; Chang-Sheng Shao; Ming-Wei Li; Li Wang; Han Wang; Gen-Hai Zhao; Peng Wang

doi:10.1101/2022.04.11.487850

New Results

Rational design by structural biology of industrializable, long-acting antihyperglycemic GLP-1 receptor agonists

Lei Sun, Zhi-Ming Zheng, Chang-Sheng Shao, Ming-Wei Li, Li Wang, Han Wang, Gen-Hai Zhao, Peng Wang

doi: https://doi.org/10.1101/2022.04.11.487850

Lei Sun

1Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei, 230031, P. R. China

2Science Island Branch of Graduate School, University of Science and Technology of China, Hefei 230026, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Zhi-Ming Zheng

1Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei, 230031, P. R. China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: zmzheng@ipp.ac.cn pengwang@ipp.ac.cn

Chang-Sheng Shao

3High Magnetic Field Laboratory, Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei, 230031, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ming-Wei Li

4MOE Key Laboratory for Membraneless Organelles and Cellular Dynamics, National Science Center for Physical Sciences at Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Li Wang

1Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei, 230031, P. R. China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Han Wang

1Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei, 230031, P. R. China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Gen-Hai Zhao

1Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei, 230031, P. R. China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Peng Wang

1Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei, 230031, P. R. China

2Science Island Branch of Graduate School, University of Science and Technology of China, Hefei 230026, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: zmzheng@ipp.ac.cn pengwang@ipp.ac.cn

Abstract
Full Text
Info/History
Metrics
Preview PDF

The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

View the discussion thread.

PreviousNext

Posted April 11, 2022.

Download PDF

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Rational design by structural biology of industrializable, long-acting antihyperglycemic GLP-1 receptor agonists

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Rational design by structural biology of industrializable, long-acting antihyperglycemic GLP-1 receptor agonists

Lei Sun, Zhi-Ming Zheng, Chang-Sheng Shao, Ming-Wei Li, Li Wang, Han Wang, Gen-Hai Zhao, Peng Wang

bioRxiv 2022.04.11.487850; doi: https://doi.org/10.1101/2022.04.11.487850

Share This Article:

Citation Tools

Rational design by structural biology of industrializable, long-acting antihyperglycemic GLP-1 receptor agonists

Lei Sun, Zhi-Ming Zheng, Chang-Sheng Shao, Ming-Wei Li, Li Wang, Han Wang, Gen-Hai Zhao, Peng Wang

bioRxiv 2022.04.11.487850; doi: https://doi.org/10.1101/2022.04.11.487850

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Bioengineering

Subject Areas

All Articles

Animal Behavior and Cognition (5612)
Biochemistry (12731)
Bioengineering (9601)
Bioinformatics (31109)
Biophysics (16027)
Cancer Biology (13097)
Cell Biology (18730)
Clinical Trials (138)
Developmental Biology (10132)
Ecology (15124)
Epidemiology (2067)
Evolutionary Biology (19326)
Genetics (12834)
Genomics (17699)
Immunology (12836)
Microbiology (30040)
Molecular Biology (12527)
Neuroscience (65444)
Paleontology (484)
Pathology (2027)
Pharmacology and Toxicology (3497)
Physiology (5422)
Plant Biology (11225)
Scientific Communication and Education (1736)
Synthetic Biology (3101)
Systems Biology (7740)
Zoology (1745)