New Results
Conserved cell-type specific signature of resilience to Alzheimer’s disease nominates role for excitatory cortical neurons
View ORCID ProfileMaria A. Telpoukhovskaia, View ORCID ProfileNiran Hadad, Brianna Gurdon, View ORCID ProfileMiko Dai, Andrew R. Ouellette, View ORCID ProfileSarah M. Neuner, View ORCID ProfileAmy R. Dunn, Shania Hansen, View ORCID ProfileYiyang Wu, View ORCID ProfileLogan Dumitrescu, View ORCID ProfileKristen M.S. O’Connell, View ORCID ProfileEric B. Dammer, View ORCID ProfileNicholas T. Seyfried, View ORCID ProfileSukalp Muzumdar, View ORCID ProfileJesse Gillis, View ORCID ProfilePaul Robson, Ji-Gang Zhang, View ORCID ProfileTimothy J. Hohman, View ORCID ProfileVivek M. Philip, Vilas Menon, View ORCID ProfileCatherine C. Kaczorowski
doi: https://doi.org/10.1101/2022.04.12.487877
Maria A. Telpoukhovskaia
1The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA
Niran Hadad
1The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA
Brianna Gurdon
1The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA
2Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA
Miko Dai
1The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA
Andrew R. Ouellette
1The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA
2Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA
Sarah M. Neuner
3Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY
Amy R. Dunn
1The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA
Shania Hansen
4Vanderbilt Memory and Alzheimer’s Center, Vanderbilt University Medical Center, Nashville, TN, USA
5Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA
Yiyang Wu
4Vanderbilt Memory and Alzheimer’s Center, Vanderbilt University Medical Center, Nashville, TN, USA
5Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA
Logan Dumitrescu
4Vanderbilt Memory and Alzheimer’s Center, Vanderbilt University Medical Center, Nashville, TN, USA
5Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA
Kristen M.S. O’Connell
1The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA
2Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA
6Neuroscience Program, Graduate School of Biomedical Science, Tufts University School of Medicine, Boston, MA, USA
Eric B. Dammer
7Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA
Nicholas T. Seyfried
7Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA
8Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA
Sukalp Muzumdar
9Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA
Jesse Gillis
9Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA
10Department of Physiology, University of Toronto, Toronto, Ontario, Canada
Paul Robson
11The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA
12Department of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, CT, USA
13Institute for Systems Genomics, University of Connecticut, Farmington, CT, USA
Ji-Gang Zhang
1The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA
Timothy J. Hohman
4Vanderbilt Memory and Alzheimer’s Center, Vanderbilt University Medical Center, Nashville, TN, USA
5Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA
Vivek M. Philip
1The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA
Vilas Menon
14Department of Neurology, Center for Translational and Computational Neuroimmunology, Columbia University Irving Medical Center, New York City, NY, USA
Catherine C. Kaczorowski
1The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA
2Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, USA
6Neuroscience Program, Graduate School of Biomedical Science, Tufts University School of Medicine, Boston, MA, USA
Posted April 13, 2022.
Conserved cell-type specific signature of resilience to Alzheimer’s disease nominates role for excitatory cortical neurons
Maria A. Telpoukhovskaia, Niran Hadad, Brianna Gurdon, Miko Dai, Andrew R. Ouellette, Sarah M. Neuner, Amy R. Dunn, Shania Hansen, Yiyang Wu, Logan Dumitrescu, Kristen M.S. O’Connell, Eric B. Dammer, Nicholas T. Seyfried, Sukalp Muzumdar, Jesse Gillis, Paul Robson, Ji-Gang Zhang, Timothy J. Hohman, Vivek M. Philip, Vilas Menon, Catherine C. Kaczorowski
bioRxiv 2022.04.12.487877; doi: https://doi.org/10.1101/2022.04.12.487877
Conserved cell-type specific signature of resilience to Alzheimer’s disease nominates role for excitatory cortical neurons
Maria A. Telpoukhovskaia, Niran Hadad, Brianna Gurdon, Miko Dai, Andrew R. Ouellette, Sarah M. Neuner, Amy R. Dunn, Shania Hansen, Yiyang Wu, Logan Dumitrescu, Kristen M.S. O’Connell, Eric B. Dammer, Nicholas T. Seyfried, Sukalp Muzumdar, Jesse Gillis, Paul Robson, Ji-Gang Zhang, Timothy J. Hohman, Vivek M. Philip, Vilas Menon, Catherine C. Kaczorowski
bioRxiv 2022.04.12.487877; doi: https://doi.org/10.1101/2022.04.12.487877
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