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Impaired immune response drives age-dependent severity of COVID-19
Julius Beer, View ORCID ProfileStefania Crotta, View ORCID ProfileAngele Breithaupt, View ORCID ProfileAnnette Ohnemus, View ORCID ProfileJan Becker, Benedikt Sachs, Lisa Kern, Miriam Llorian, Nadine Ebert, View ORCID ProfileFabien Labroussaa, Tran Thi Nhu Thao, View ORCID ProfileBettina Salome Trueeb, View ORCID ProfileJoerg Jores, View ORCID ProfileVolker Thiel, Martin Beer, View ORCID ProfileJonas Fuchs, View ORCID ProfileGeorg Kochs, View ORCID ProfileAndreas Wack, View ORCID ProfileMartin Schwemmle, View ORCID ProfileDaniel Schnepf
doi: https://doi.org/10.1101/2022.04.21.489072
Julius Beer
1Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany
Stefania Crotta
2Immunoregulation Laboratory, The Francis Crick Institute, London, UK
Angele Breithaupt
3Department of Experimental Animal Facilities and Biorisk Management, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
Annette Ohnemus
1Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany
Jan Becker
1Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany
Benedikt Sachs
1Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany
Lisa Kern
1Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany
Miriam Llorian
4Bioinformatics and Biostatistics, The Francis Crick Institute, London, UK
Nadine Ebert
5Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
6Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Fabien Labroussaa
6Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
7Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Tran Thi Nhu Thao
5Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
6Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
8Graduate School for Biomedical Science, University of Bern, Bern, Switzerland
Bettina Salome Trueeb
6Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
7Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Joerg Jores
6Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
7Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Volker Thiel
5Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland
6Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
9Multidisciplinary Center for Infectious Diseases, University of Bern, Switzerland
Martin Beer
10Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
Jonas Fuchs
1Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany
Georg Kochs
1Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany
Andreas Wack
2Immunoregulation Laboratory, The Francis Crick Institute, London, UK
Martin Schwemmle
1Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany
11Faculty of Medicine, University of Freiburg, Freiburg, Germany
Daniel Schnepf
1Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany
Article usage
Posted April 22, 2022.
Impaired immune response drives age-dependent severity of COVID-19
Julius Beer, Stefania Crotta, Angele Breithaupt, Annette Ohnemus, Jan Becker, Benedikt Sachs, Lisa Kern, Miriam Llorian, Nadine Ebert, Fabien Labroussaa, Tran Thi Nhu Thao, Bettina Salome Trueeb, Joerg Jores, Volker Thiel, Martin Beer, Jonas Fuchs, Georg Kochs, Andreas Wack, Martin Schwemmle, Daniel Schnepf
bioRxiv 2022.04.21.489072; doi: https://doi.org/10.1101/2022.04.21.489072
Impaired immune response drives age-dependent severity of COVID-19
Julius Beer, Stefania Crotta, Angele Breithaupt, Annette Ohnemus, Jan Becker, Benedikt Sachs, Lisa Kern, Miriam Llorian, Nadine Ebert, Fabien Labroussaa, Tran Thi Nhu Thao, Bettina Salome Trueeb, Joerg Jores, Volker Thiel, Martin Beer, Jonas Fuchs, Georg Kochs, Andreas Wack, Martin Schwemmle, Daniel Schnepf
bioRxiv 2022.04.21.489072; doi: https://doi.org/10.1101/2022.04.21.489072
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