Upregulation of Somatostatin Receptor Type 2 in a Receptor-Deficient In Vivo Pancreatic Neuroendocrine Tumor Model Improves Tumor Response to Targeted 177Lu-DOTATATE

Rupali Sharma; Bhargav Earla; Kwamena Baidoo; Martha A. Zeiger; James P. Madigan; Freddy E. Escorcia; Samira M. Sadowski

doi:10.1101/2022.04.25.489401

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Upregulation of Somatostatin Receptor Type 2 in a Receptor-Deficient In Vivo Pancreatic Neuroendocrine Tumor Model Improves Tumor Response to Targeted ¹⁷⁷Lu-DOTATATE

Rupali Sharma, Bhargav Earla, Kwamena Baidoo, Martha A. Zeiger, James P. Madigan, View ORCID ProfileFreddy E. Escorcia, Samira M. Sadowski

doi: https://doi.org/10.1101/2022.04.25.489401

Rupali Sharma

1Endocrine Surgery Section, Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, NIH, 10 Center Drive, Bldg 10, Bethesda, MD, USA

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Bhargav Earla

1Endocrine Surgery Section, Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, NIH, 10 Center Drive, Bldg 10, Bethesda, MD, USA

2UAB Heersink School of Medicine, 1670 University Blvd, Birmingham, AL, USA

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Kwamena Baidoo

3Molecular Imaging Branch, Center for Cancer Research, National Cancer Institute, NIH, 10 Center Drive, Bldg 10, Bethesda, MD, USA

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Martha A. Zeiger

4Office of Surgeon Scientists Programs, Center for Cancer Research, National Cancer Institute, NIH, Bldg 31, Bethesda, MD, USA

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James P. Madigan

1Endocrine Surgery Section, Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, NIH, 10 Center Drive, Bldg 10, Bethesda, MD, USA

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Freddy E. Escorcia

3Molecular Imaging Branch, Center for Cancer Research, National Cancer Institute, NIH, 10 Center Drive, Bldg 10, Bethesda, MD, USA

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ORCID record for Freddy E. Escorcia

Samira M. Sadowski

1Endocrine Surgery Section, Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, NIH, 10 Center Drive, Bldg 10, Bethesda, MD, USA

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For correspondence: samira.sadowski@nih.gov

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Posted April 26, 2022.

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Upregulation of Somatostatin Receptor Type 2 in a Receptor-Deficient In Vivo Pancreatic Neuroendocrine Tumor Model Improves Tumor Response to Targeted ¹⁷⁷Lu-DOTATATE

Rupali Sharma, Bhargav Earla, Kwamena Baidoo, Martha A. Zeiger, James P. Madigan, Freddy E. Escorcia, Samira M. Sadowski

bioRxiv 2022.04.25.489401; doi: https://doi.org/10.1101/2022.04.25.489401

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Upregulation of Somatostatin Receptor Type 2 in a Receptor-Deficient In Vivo Pancreatic Neuroendocrine Tumor Model Improves Tumor Response to Targeted ¹⁷⁷Lu-DOTATATE

Rupali Sharma, Bhargav Earla, Kwamena Baidoo, Martha A. Zeiger, James P. Madigan, Freddy E. Escorcia, Samira M. Sadowski

bioRxiv 2022.04.25.489401; doi: https://doi.org/10.1101/2022.04.25.489401

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