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CLARITY increases sensitivity and specificity of fluorescence immunostaining in long-term archived human brain tissue
Sarah Woelfle, Dhruva Deshpande, Simone Feldengut, View ORCID ProfileFrancesco Roselli, Karl Deisseroth, View ORCID ProfileJens Michaelis, Tobias M. Boeckers, View ORCID ProfileMichael Schön
doi: https://doi.org/10.1101/2022.04.27.489700
Sarah Woelfle
1Institute for Anatomy and Cell Biology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany
2International Graduate School in Molecular Medicine Ulm, IGradU, 89081 Ulm, Germany
Dhruva Deshpande
3Institute of Biophysics, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany
4Chemical and Systems Biology Department, Stanford School of Medicine, 269 Campus Drive, Stanford, CA 94305, USA
Simone Feldengut
5Clinical Neuroanatomy Section/Department of Neurology, Center for Biomedical Research, Ulm University, Helmholtzstraße 8/1, 89081 Ulm, Germany
Francesco Roselli
6Department of Neurology, Ulm University, 89081 Ulm, Germany
7Deutsches Zentrum für Neurodegenerative Erkrankungen, DZNE, Ulm site, 89081 Ulm, Germany
Karl Deisseroth
8Department of Bioengineering, Stanford University, Stanford, CA 94305, USA; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford, CA 94305, USA
Jens Michaelis
3Institute of Biophysics, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany
Tobias M. Boeckers
1Institute for Anatomy and Cell Biology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany
7Deutsches Zentrum für Neurodegenerative Erkrankungen, DZNE, Ulm site, 89081 Ulm, Germany
Michael Schön
1Institute for Anatomy and Cell Biology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany
Article usage
Posted April 29, 2022.
CLARITY increases sensitivity and specificity of fluorescence immunostaining in long-term archived human brain tissue
Sarah Woelfle, Dhruva Deshpande, Simone Feldengut, Francesco Roselli, Karl Deisseroth, Jens Michaelis, Tobias M. Boeckers, Michael Schön
bioRxiv 2022.04.27.489700; doi: https://doi.org/10.1101/2022.04.27.489700
CLARITY increases sensitivity and specificity of fluorescence immunostaining in long-term archived human brain tissue
Sarah Woelfle, Dhruva Deshpande, Simone Feldengut, Francesco Roselli, Karl Deisseroth, Jens Michaelis, Tobias M. Boeckers, Michael Schön
bioRxiv 2022.04.27.489700; doi: https://doi.org/10.1101/2022.04.27.489700
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