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DysRegNet: Patient-specific and confounder-aware dysregulated network inference

Olga Lazareva, View ORCID ProfileZakaria Louadi, Johannes Kersting, View ORCID ProfileJan Baumbach, View ORCID ProfileDavid B. Blumenthal, View ORCID ProfileMarkus List
doi: https://doi.org/10.1101/2022.04.29.490015
Olga Lazareva
1Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany
5Division of Computational Genomics and Systems Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany
6European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany
6European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany
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Zakaria Louadi
1Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany
2Institute for Computational Systems Biology, University of Hamburg, Hamburg, Germany
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Johannes Kersting
1Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany
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Jan Baumbach
2Institute for Computational Systems Biology, University of Hamburg, Hamburg, Germany
3Department of Mathematics and Computer Science, University of Southern Denmark, Odense, Denmark
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David B. Blumenthal
4Department Artificial Intelligence in Biomedical Engineering (AIBE), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany
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Markus List
1Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany
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  • ORCID record for Markus List
  • For correspondence: markus.list@tum.de
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Article Information

doi 
https://doi.org/10.1101/2022.04.29.490015
History 
  • May 1, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Olga Lazareva1,5,6,7,*,
  2. Zakaria Louadi1,2,*,
  3. Johannes Kersting1,
  4. Jan Baumbach2,3,
  5. David B. Blumenthal4 and
  6. Markus List1,✉
  1. 1Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany
  2. 2Institute for Computational Systems Biology, University of Hamburg, Hamburg, Germany
  3. 3Department of Mathematics and Computer Science, University of Southern Denmark, Odense, Denmark
  4. 4Department Artificial Intelligence in Biomedical Engineering (AIBE), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany
  5. 5Division of Computational Genomics and Systems Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany
  6. 5Junior Clinical Cooperation Unit Multiparametric methods for early detection of prostate cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany
  7. 6European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany
  1. ↵✉Correspondence: markus.list{at}tum.de
  1. ↵* These authors contributed equally

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Posted May 01, 2022.
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DysRegNet: Patient-specific and confounder-aware dysregulated network inference
Olga Lazareva, Zakaria Louadi, Johannes Kersting, Jan Baumbach, David B. Blumenthal, Markus List
bioRxiv 2022.04.29.490015; doi: https://doi.org/10.1101/2022.04.29.490015
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DysRegNet: Patient-specific and confounder-aware dysregulated network inference
Olga Lazareva, Zakaria Louadi, Johannes Kersting, Jan Baumbach, David B. Blumenthal, Markus List
bioRxiv 2022.04.29.490015; doi: https://doi.org/10.1101/2022.04.29.490015

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