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Characterizing ketamine-induced dissociation using human intracranial neurophysiology: brain dynamics, network activity, and interactions with propofol
Fangyun Tian, Laura D. Lewis, David W. Zhou, Gustavo Balanza Villegas, View ORCID ProfileAngelique C. Paulk, View ORCID ProfileRina Zelmann, Noam Peled, Daniel Soper, Laura A. Santa Cruz Mercado, Robert A. Peterfreund, Linda S. Aglio, Emad N. Eskandar, G Rees Cosgrove, Ziv M. Williams, View ORCID ProfileRobert M. Richardson, Emery N. Brown, View ORCID ProfileOluwaseun Akeju, View ORCID ProfileSydney S. Cash, Patrick L. Purdon
doi: https://doi.org/10.1101/2022.05.02.490333
Fangyun Tian
1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Laura D. Lewis
2Department of Biomedical Engineering, Boston University, Boston, MA, USA
David W. Zhou
1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
3Department of Brain and Cognitive Sciences. Massachusetts Institute of Technology. Cambridge, MA, USA
Gustavo Balanza Villegas
1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Angelique C. Paulk
4Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
5Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Boston, MA, USA
Rina Zelmann
4Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
5Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Boston, MA, USA
Noam Peled
6Department of Radiology, MGH/HST Martinos Center for Biomedical Imaging and Harvard Medical School, Boston, MA, USA
Daniel Soper
4Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Laura A. Santa Cruz Mercado
1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Robert A. Peterfreund
1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Linda S. Aglio
7Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA, USA
Emad N. Eskandar
8Department of Neurological Surgery, Albert Einstein College of Medicine, Bronx, NY, USA
G Rees Cosgrove
9Department of Neurological Surgery, Brigham and Women’s Hospital, Boston, MA, USA
Ziv M. Williams
10Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Robert M. Richardson
10Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Emery N. Brown
1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
11Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA
Oluwaseun Akeju
1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Sydney S. Cash
4Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
5Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Boston, MA, USA
Patrick L. Purdon
1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Article usage
Posted May 04, 2022.
Characterizing ketamine-induced dissociation using human intracranial neurophysiology: brain dynamics, network activity, and interactions with propofol
Fangyun Tian, Laura D. Lewis, David W. Zhou, Gustavo Balanza Villegas, Angelique C. Paulk, Rina Zelmann, Noam Peled, Daniel Soper, Laura A. Santa Cruz Mercado, Robert A. Peterfreund, Linda S. Aglio, Emad N. Eskandar, G Rees Cosgrove, Ziv M. Williams, Robert M. Richardson, Emery N. Brown, Oluwaseun Akeju, Sydney S. Cash, Patrick L. Purdon
bioRxiv 2022.05.02.490333; doi: https://doi.org/10.1101/2022.05.02.490333
Characterizing ketamine-induced dissociation using human intracranial neurophysiology: brain dynamics, network activity, and interactions with propofol
Fangyun Tian, Laura D. Lewis, David W. Zhou, Gustavo Balanza Villegas, Angelique C. Paulk, Rina Zelmann, Noam Peled, Daniel Soper, Laura A. Santa Cruz Mercado, Robert A. Peterfreund, Linda S. Aglio, Emad N. Eskandar, G Rees Cosgrove, Ziv M. Williams, Robert M. Richardson, Emery N. Brown, Oluwaseun Akeju, Sydney S. Cash, Patrick L. Purdon
bioRxiv 2022.05.02.490333; doi: https://doi.org/10.1101/2022.05.02.490333
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