Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Population Genomics of Stone Age Eurasia

View ORCID ProfileMorten E. Allentoft, View ORCID ProfileMartin Sikora, View ORCID ProfileAlba Refoyo-Martínez, View ORCID ProfileEvan K. Irving-Pease, View ORCID ProfileAnders Fischer, View ORCID ProfileWilliam Barrie, Andrés Ingason, Jesper Stenderup, View ORCID ProfileKarl-Göran Sjögren, Alice Pearson, View ORCID ProfileBarbara Mota, Bettina Schulz Paulsson, Alma Halgren, View ORCID ProfileRuairidh Macleod, View ORCID ProfileMarie Louise Schjellerup Jørkov, Fabrice Demeter, View ORCID ProfileMaria Novosolov, Lasse Sørensen, Poul-Otto Nielsen, View ORCID ProfileRasmus H.A. Henriksen, View ORCID ProfileTharsika Vimala, View ORCID ProfileHugh McColl, View ORCID ProfileAshot Margaryan, Melissa Ilardo, Andrew Vaughn, Morten Fischer Mortensen, Anne Birgitte Nielsen, Mikkel Ulfeldt Hede, Peter Rasmussen, View ORCID ProfileLasse Vinner, Gabriel Renaud, Aaron Stern, Theis Zetner Trolle Jensen, View ORCID ProfileNiels Nørkjær Johannsen, View ORCID ProfileGabriele Scorrano, View ORCID ProfileHannes Schroeder, Per Lysdahl, View ORCID ProfileAbigail Daisy Ramsøe, Andrei Skorobogatov, Andrew Joseph Schork, View ORCID ProfileAnders Rosengren, View ORCID ProfileAnthony Ruter, View ORCID ProfileAlan Outram, View ORCID ProfileAleksey A. Timoshenko, View ORCID ProfileAlexandra Buzhilova, Alfredo Coppa, View ORCID ProfileAlisa Zubova, View ORCID ProfileAna Maria Silva, Anders J. Hansen, View ORCID ProfileAndrey Gromov, Andrey Logvin, Anne Birgitte Gotfredsen, Bjarne Henning Nielsen, View ORCID ProfileBorja González-Rabanal, Carles Lalueza-Fox, Catriona J. McKenzie, Charleen Gaunitz, Concepción Blasco, Corina Liesau, Cristina Martinez-Labarga, Dmitri V. Pozdnyakov, David Cuenca-Solana, David O. Lordkipanidze, Dmitri En’shin, Domingo C. Salazar-García, T. Douglas Price, Dušan Borić, Elena Kostyleva, Elizaveta V. Veselovskaya, Emma R. Usmanova, View ORCID ProfileEnrico Cappellini, Erik Brinch Petersen, Esben Kannegaard, Francesca Radina, View ORCID ProfileFulya Eylem Yediay, Henri Duday, View ORCID ProfileIgor Gutiérrez-Zugasti, Inna Potekhina, Irina Shevnina, View ORCID ProfileIsin Altinkaya, Jean Guilaine, View ORCID ProfileJesper Hansen, View ORCID ProfileJoan Emili Aura Tortosa, View ORCID ProfileJoão Zilhão, Jorge Vega, Kristoffer Buck Pedersen, Krzysztof Tunia, View ORCID ProfileLei Zhao, Liudmila N. Mylnikova, Lars Larsson, Laure Metz, View ORCID ProfileLevon Yeppiskoposyan, Lisbeth Pedersen, Lucia Sarti, View ORCID ProfileLudovic Orlando, View ORCID ProfileLudovic Slimak, Lutz Klassen, View ORCID ProfileMalou Blank, View ORCID ProfileManuel González-Morales, Mara Silvestrini, Maria Vretemark, Marina S. Nesterova, View ORCID ProfileMarina Rykun, Mario Federico Rolfo, View ORCID ProfileMarzena Szmyt, Marcin Przybyła, Mauro Calattini, View ORCID ProfileMikhail Sablin, Miluše Dobisíková, Morten Meldgaard, View ORCID ProfileMorten Johansen, View ORCID ProfileNatalia Berezina, Nick Card, Nikolai A. Saveliev, View ORCID ProfileOlga Poshekhonova, Olga Rickards, View ORCID ProfileOlga V. Lozovskaya, Otto Christian Uldum, Paola Aurino, View ORCID ProfilePavel Kosintsev, Patrice Courtaud, Patricia Ríos, Peder Mortensen, Per Lotz, Per Åke Persson, View ORCID ProfilePernille Bangsgaard, Peter de Barros Damgaard, Peter Vang Petersen, View ORCID ProfilePilar Prieto Martinez, Piotr Włodarczak, Roman V. Smolyaninov, View ORCID ProfileRikke Maring, Roberto Menduiña, Ruben Badalyan, View ORCID ProfileRune Iversen, Ruslan Turin, Sergey Vasilyiev, Sidsel Wåhlin, View ORCID ProfileSvetlana Borutskaya, Svetlana Skochina, Søren Anker Sørensen, Søren H. Andersen, Thomas Jørgensen, Yuri B. Serikov, Vyacheslav I. Molodin, View ORCID ProfileVaclav Smrcka, Victor Merz, Vivek Appadurai, View ORCID ProfileVyacheslav Moiseyev, View ORCID ProfileYvonne Magnusson, Kurt H. Kjær, View ORCID ProfileNiels Lynnerup, View ORCID ProfileDaniel J. Lawson, View ORCID ProfilePeter H. Sudmant, Simon Rasmussen, Thorfinn Korneliussen, View ORCID ProfileRichard Durbin, View ORCID ProfileRasmus Nielsen, View ORCID ProfileOlivier Delaneau, View ORCID ProfileThomas Werge, View ORCID ProfileFernando Racimo, Kristian Kristiansen, View ORCID ProfileEske Willerslev
doi: https://doi.org/10.1101/2022.05.04.490594
Morten E. Allentoft
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
2Trace and Environmental DNA (TrEnD) Laboratory, School of Molecular and Life Sciences, Curtin University, Perth, Australia.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Morten E. Allentoft
  • For correspondence: morten.allentoft@curtin.edu.au martin.sikora@sund.ku.dk ew482@cam.ac.uk
Martin Sikora
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Martin Sikora
  • For correspondence: morten.allentoft@curtin.edu.au martin.sikora@sund.ku.dk ew482@cam.ac.uk
Alba Refoyo-Martínez
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Alba Refoyo-Martínez
Evan K. Irving-Pease
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Evan K. Irving-Pease
Anders Fischer
3Department of Historical Studies, University of Gothenburg, Gothenburg, Sweden.
4Sealand Archaeology, Gl. Roesnaesvej 27, 4400 Kalundborg, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Anders Fischer
William Barrie
5GeoGenetics Group, Department of Zoology, University of Cambridge, Cambridge, UK.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for William Barrie
Andrés Ingason
6Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Roskilde, Denmark
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jesper Stenderup
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Karl-Göran Sjögren
3Department of Historical Studies, University of Gothenburg, Gothenburg, Sweden.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Karl-Göran Sjögren
Alice Pearson
7Department of Genetics, University of Cambridge, Cambridge, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Barbara Mota
8Department of Computational Biology, University of Lausanne, Switzerland
9Swiss Institute of Bioinformatics, University of Lausanne, Switzerland.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Barbara Mota
Bettina Schulz Paulsson
3Department of Historical Studies, University of Gothenburg, Gothenburg, Sweden.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Alma Halgren
10Department of Integrative Biology, University of California, Berkeley, USA.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ruairidh Macleod
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
5GeoGenetics Group, Department of Zoology, University of Cambridge, Cambridge, UK.
11Research department of Genetics, Evolution and Environment, University College London, London, UK.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ruairidh Macleod
Marie Louise Schjellerup Jørkov
12Laboratory of Biological Anthropology, Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Marie Louise Schjellerup Jørkov
Fabrice Demeter
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
13Muséum national d’Histoire naturelle, CNRS, Université de Paris, Musée de l’Homme, Paris, France
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Maria Novosolov
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Maria Novosolov
Lasse Sørensen
14The National Museum of Denmark, Ny Vestergade 10, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Poul-Otto Nielsen
14The National Museum of Denmark, Ny Vestergade 10, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rasmus H.A. Henriksen
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Rasmus H.A. Henriksen
Tharsika Vimala
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Tharsika Vimala
Hugh McColl
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Hugh McColl
Ashot Margaryan
15Section for Evolutionary Genomics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark
16Centre for Evolutionary Hologenomics, University of Copenhagen, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ashot Margaryan
Melissa Ilardo
17Anthropology Department, University of Utah, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andrew Vaughn
18Center for Computational Biology, University of California, Berkeley, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Morten Fischer Mortensen
14The National Museum of Denmark, Ny Vestergade 10, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anne Birgitte Nielsen
19Department of Geology, Lund University, Lund, Sweden.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mikkel Ulfeldt Hede
20Tårnby Gymnasium og HF, Kastrup, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Peter Rasmussen
14The National Museum of Denmark, Ny Vestergade 10, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lasse Vinner
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Lasse Vinner
Gabriel Renaud
21Department of Health Technology, Section of Bioinformatics, Technical University of Denmark, Kongens Lyngby, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Aaron Stern
18Center for Computational Biology, University of California, Berkeley, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Theis Zetner Trolle Jensen
15Section for Evolutionary Genomics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Niels Nørkjær Johannsen
22Department of Archaeology and Heritage Studies, Aarhus University, Aarhus, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Niels Nørkjær Johannsen
Gabriele Scorrano
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Gabriele Scorrano
Hannes Schroeder
15Section for Evolutionary Genomics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Hannes Schroeder
Per Lysdahl
23Vendsyssel Historiske Museum, DK-9800 Hjørring, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Abigail Daisy Ramsøe
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Abigail Daisy Ramsøe
Andrei Skorobogatov
24Terra Ltd., Letchik Zlobin St. 20, Voronezh, 394055, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andrew Joseph Schork
6Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Roskilde, Denmark
25Neurogenomics Division, The Translational Genomics Research Institute (TGEN), Phoenix, AZ, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anders Rosengren
6Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Roskilde, Denmark
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Anders Rosengren
Anthony Ruter
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Anthony Ruter
Alan Outram
26Department of Archaeology, University of Exeter, Exeter, UK.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Alan Outram
Aleksey A. Timoshenko
27Institute of Archaeology and Ethnography, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Aleksey A. Timoshenko
Alexandra Buzhilova
28Research Institute and Museum of Anthropology, Lomonosov Moscow State University, Mokhovaya str. 11, Moscow, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Alexandra Buzhilova
Alfredo Coppa
29Department of Environmental Biology, Sapienza University of Rome, Rome, Italy.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Alisa Zubova
30Peter the Great Museum of Anthropology and Ethnography (Kunstkamera), Russian Academy of Sciences, Saint Petersburg, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Alisa Zubova
Ana Maria Silva
31CIAS, Department of Life Science, University of Coimbra, Coimbra, Portugal.
59UNIARQ, University of Lisbon, Lisbon, Portugal.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ana Maria Silva
Anders J. Hansen
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andrey Gromov
30Peter the Great Museum of Anthropology and Ethnography (Kunstkamera), Russian Academy of Sciences, Saint Petersburg, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Andrey Gromov
Andrey Logvin
32Kostanay Regional University A. Baitursynov, Kostanay, Kazakhstan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anne Birgitte Gotfredsen
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bjarne Henning Nielsen
33Vesthimmerlands Museum, Søndergade 44, Aars, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Borja González-Rabanal
34Grupo EvoAdapta, Departamento de Ciencias Históricas, Universidad de Cantabria, Santander, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Borja González-Rabanal
Carles Lalueza-Fox
35Institute of Evolutionary Biology, CSIC-Universitat Pompeu Fabra, Barcelona, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Catriona J. McKenzie
26Department of Archaeology, University of Exeter, Exeter, UK.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Charleen Gaunitz
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Concepción Blasco
36Departamento de Prehistoria y Arqueología Department, Universidad Autónoma de Madrid, Madrid, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Corina Liesau
36Departamento de Prehistoria y Arqueología Department, Universidad Autónoma de Madrid, Madrid, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Cristina Martinez-Labarga
37Department of Biology, University of Rome “Tor Vergata”, Rome, Italy.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dmitri V. Pozdnyakov
27Institute of Archaeology and Ethnography, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David Cuenca-Solana
38Instituto Internacional de Investigaciones Prehistóricas de Cantabria, Universidad de Cantabria, Santander, Spain.
39Centre de Recherche en Archéologie, Archeosciences, Histoire (CReAAH), UMR-6566 CNRS, Rennes, France.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David O. Lordkipanidze
40Georgian National Museum, Tbilisi, Georgia.
41Tbilisi State University, Tbilisi, Georgia.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dmitri En’shin
42IPND, Tyumen Scientific Centre, Siberian Branch of the Russian Academy of Sciences, Tyumen, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Domingo C. Salazar-García
43Departament de Prehistòria, Arqueologia i Història Antiga, Universitat de València, València, Spain.
44Department of Geological Sciences, University of Cape Town, Cape Town, South Africa.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T. Douglas Price
45Laboratory for Archaeological Chemistry, Department of Anthropology, University of Wisconsin-Madison, Madison, USA.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dušan Borić
29Department of Environmental Biology, Sapienza University of Rome, Rome, Italy.
46Department of Anthropology, New York University, New York, USA.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Elena Kostyleva
47Institute of Humanities, Ivanovo State University, Ivanovo, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Elizaveta V. Veselovskaya
48Institute of Ethnology and Anthropology, Russian Academy of Sciences, Moscow, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Emma R. Usmanova
49Saryarka Archaeological Institute, Buketov Karaganda University, Karaganda, Kazakhstan.
50South Ural State University, Chelyabinsk, Russia.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Enrico Cappellini
15Section for Evolutionary Genomics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Enrico Cappellini
Erik Brinch Petersen
51The Saxo Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Esben Kannegaard
52Museum Østjylland, Stemannsgade 2, Randers, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Francesca Radina
53Soprintendenza Archeologia Belle Arti e Paesaggio per la Città Metropolitana di Bari, Via Pier l’Eremita, 25, 70122, Bari, Italy.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Fulya Eylem Yediay
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Fulya Eylem Yediay
Henri Duday
54UMR 5199 PACEA, CNRS, Université de Bordeaux, 33615 Pessac, France.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Igor Gutiérrez-Zugasti
38Instituto Internacional de Investigaciones Prehistóricas de Cantabria, Universidad de Cantabria, Santander, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Igor Gutiérrez-Zugasti
Inna Potekhina
55Institute of Archaeology, National Academy of Sciences of Ukraine, Kyiv, Ukraine.
56National University of Kyiv-Mohyla Academy, Kyiv, Ukraine.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Irina Shevnina
32Kostanay Regional University A. Baitursynov, Kostanay, Kazakhstan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Isin Altinkaya
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Isin Altinkaya
Jean Guilaine
57Collège de France, 75231 Paris cedex 05, France.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jesper Hansen
58Odense City Museums, Overgade 48, Odense, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jesper Hansen
Joan Emili Aura Tortosa
43Departament de Prehistòria, Arqueologia i Història Antiga, Universitat de València, València, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Joan Emili Aura Tortosa
João Zilhão
59UNIARQ, University of Lisbon, Lisbon, Portugal.
60ICREA, University of Barcelona, Barcelona, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for João Zilhão
Jorge Vega
61ARGEA Consultores SL, C. de San Crispín, Madrid, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kristoffer Buck Pedersen
62Museum Sydøstdanmark, Algade 97, 4760 Vordingborg, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Krzysztof Tunia
63Institute of Archaeology and Ethnology, Polish Academy of Sciences, Kraków, Poland.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lei Zhao
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Lei Zhao
Liudmila N. Mylnikova
27Institute of Archaeology and Ethnography, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lars Larsson
64Department of Archaeology and Ancient History, Lund University, Lund, Sweden.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Laure Metz
65CNRS UMR 5608, Toulouse Jean Jaurès University, Maison de la Recherche, 5 Allées Antonio Machado, 31058 Toulouse, Cedex 9, France.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Levon Yeppiskoposyan
66Institute of Molecular Biology, National Academy of Sciences, Yerevan, Armenia.
93Russian-Armenian University, Yerevan, Armenia.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Levon Yeppiskoposyan
Lisbeth Pedersen
67HistorieUdvikler, Gl. Roesnaesvej 27, DK-4400 Kalundborg, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lucia Sarti
68Department of history and cultural heritage, University of Siena, Siena, Italy.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ludovic Orlando
69Centre d’Anthropobiologie et de Génomique de Toulouse, CNRS UMR 5288, Université Paul Sabatier, Toulouse, France.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ludovic Orlando
Ludovic Slimak
65CNRS UMR 5608, Toulouse Jean Jaurès University, Maison de la Recherche, 5 Allées Antonio Machado, 31058 Toulouse, Cedex 9, France.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ludovic Slimak
Lutz Klassen
52Museum Østjylland, Stemannsgade 2, Randers, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Malou Blank
3Department of Historical Studies, University of Gothenburg, Gothenburg, Sweden.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Malou Blank
Manuel González-Morales
38Instituto Internacional de Investigaciones Prehistóricas de Cantabria, Universidad de Cantabria, Santander, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Manuel González-Morales
Mara Silvestrini
70Soprintendenza per i Beni Archeologici delle Marche, Via Birarelli 18, 60100, Ancona, Italy.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Maria Vretemark
71Västergötlands museum, Stadsträdgården, Skara, Sweden.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marina S. Nesterova
27Institute of Archaeology and Ethnography, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marina Rykun
72Cabinet of Anthropology, Tomsk State University, Tomsk, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Marina Rykun
Mario Federico Rolfo
73Department of History, Humanities and Society, University of Rome “Tor Vergata”, Rome, Italy.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marzena Szmyt
74Institute for Eastern Research, Adam Mickiewicz University in Poznań, Poznań, Poland.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Marzena Szmyt
Marcin Przybyła
75Institute of Archaeology, Jagiellonian University, Ul. Gołębia 11, 31-007, Kraków, Poland.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mauro Calattini
68Department of history and cultural heritage, University of Siena, Siena, Italy.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mikhail Sablin
76Zoological Institute of Russian Academy of Sciences, Universitetskaya nab. 1, 199034, St. Petersburg, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Mikhail Sablin
Miluše Dobisíková
77Department of Anthropology, Czech National Museum, Prague, Czech Republic.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Morten Meldgaard
78Department of Health and Nature, University of Greenland, Greenland.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Morten Johansen
79The Viking Ship Museum, Vindeboder 12, Roskilde, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Morten Johansen
Natalia Berezina
28Research Institute and Museum of Anthropology, Lomonosov Moscow State University, Mokhovaya str. 11, Moscow, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Natalia Berezina
Nick Card
80Archaeology Institute, University of Highlands and Islands, Scotland, UK.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nikolai A. Saveliev
81Scientific Research Center “Baikal region”, Irkutsk State University; 1, K. Marx st., Irkutsk, 664003, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Olga Poshekhonova
42IPND, Tyumen Scientific Centre, Siberian Branch of the Russian Academy of Sciences, Tyumen, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Olga Poshekhonova
Olga Rickards
37Department of Biology, University of Rome “Tor Vergata”, Rome, Italy.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Olga V. Lozovskaya
82Laboratory for Experimental Traceology, Institute for the History of Material Culture of the Russian Academy of Sciences, Dvortsovaya nab., 18, 191186, St. Petersburg, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Olga V. Lozovskaya
Otto Christian Uldum
79The Viking Ship Museum, Vindeboder 12, Roskilde, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Paola Aurino
83Soprintendenza Archeologia, Belle Arti e Paesaggio per la provincia di Cosenza, Cosenza, Italy.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pavel Kosintsev
84Paleoecology Laboratory, Institute of Plant and Animal Ecology, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation.
85Department of History of the Institute of Humanities, Ural Federal University, Ekaterinburg, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Pavel Kosintsev
Patrice Courtaud
54UMR 5199 PACEA, CNRS, Université de Bordeaux, 33615 Pessac, France.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Patricia Ríos
36Departamento de Prehistoria y Arqueología Department, Universidad Autónoma de Madrid, Madrid, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Peder Mortensen
86Centre for the Study of Early Agricultural Societies, Department of Cross-Cultural and Regional Studies, University of Copenhagen, 2300 Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Per Lotz
87Museum Nordsjælland, Frederiksgade 9, 3400 Hillerød.
88Museum Vestsjælland, Klosterstræde 18, 4300 Holbæk, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Per Åke Persson
89Museum of Cultural History, University of Oslo, P.O. Box 6762. St. Olavs Plass NO-0130 Oslo, Norway.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pernille Bangsgaard
90ArchaeoScience, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Pernille Bangsgaard
Peter de Barros Damgaard
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Peter Vang Petersen
14The National Museum of Denmark, Ny Vestergade 10, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pilar Prieto Martinez
91Department of History, University of Santiago de Compostela, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Pilar Prieto Martinez
Piotr Włodarczak
63Institute of Archaeology and Ethnology, Polish Academy of Sciences, Kraków, Poland.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Roman V. Smolyaninov
92Lipetsk Regional Scientific Public Organisation “Archaeological Research”, Lipetsk, Russian Federation. Institute of Archaeology and Ethnography, National Academy of Sciences, Yerevan, Armenia.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rikke Maring
22Department of Archaeology and Heritage Studies, Aarhus University, Aarhus, Denmark.
52Museum Østjylland, Stemannsgade 2, Randers, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Rikke Maring
Roberto Menduiña
61ARGEA Consultores SL, C. de San Crispín, Madrid, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ruben Badalyan
91Department of History, University of Santiago de Compostela, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rune Iversen
51The Saxo Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Rune Iversen
Ruslan Turin
24Terra Ltd., Letchik Zlobin St. 20, Voronezh, 394055, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sergey Vasilyiev
27Institute of Archaeology and Ethnography, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sidsel Wåhlin
23Vendsyssel Historiske Museum, DK-9800 Hjørring, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Svetlana Borutskaya
28Research Institute and Museum of Anthropology, Lomonosov Moscow State University, Mokhovaya str. 11, Moscow, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Svetlana Borutskaya
Svetlana Skochina
42IPND, Tyumen Scientific Centre, Siberian Branch of the Russian Academy of Sciences, Tyumen, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Søren Anker Sørensen
87Museum Nordsjælland, Frederiksgade 9, 3400 Hillerød.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Søren H. Andersen
94Moesgaard Museum, Moesgård Allé 15, Højbjerg, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thomas Jørgensen
87Museum Nordsjælland, Frederiksgade 9, 3400 Hillerød.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yuri B. Serikov
95Nizhny Tagil State Socio-Pedagogical Institute, Nizhny Tagil, Russia.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vyacheslav I. Molodin
27Institute of Archaeology and Ethnography, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vaclav Smrcka
96Institute for History of Medicine, First Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Vaclav Smrcka
Victor Merz
97Centre for Archaeological Research Toraighyrov University, Pavlodar, Kazakhstan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vivek Appadurai
6Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Roskilde, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vyacheslav Moiseyev
30Peter the Great Museum of Anthropology and Ethnography (Kunstkamera), Russian Academy of Sciences, Saint Petersburg, Russian Federation.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Vyacheslav Moiseyev
Yvonne Magnusson
98Malmö Museer, Malmöhusvägen 6, Malmö, Sweden.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Yvonne Magnusson
Kurt H. Kjær
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Niels Lynnerup
12Laboratory of Biological Anthropology, Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Niels Lynnerup
Daniel J. Lawson
99Institute of Statistical Sciences, School of Mathematics, University of Bristol, Bristol, UK.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Daniel J. Lawson
Peter H. Sudmant
10Department of Integrative Biology, University of California, Berkeley, USA.
18Center for Computational Biology, University of California, Berkeley, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Peter H. Sudmant
Simon Rasmussen
100Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thorfinn Korneliussen
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Richard Durbin
7Department of Genetics, University of Cambridge, Cambridge, UK
101Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Richard Durbin
Rasmus Nielsen
10Department of Integrative Biology, University of California, Berkeley, USA.
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Rasmus Nielsen
Olivier Delaneau
8Department of Computational Biology, University of Lausanne, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Olivier Delaneau
Thomas Werge
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
6Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Roskilde, Denmark
102Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen N, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Thomas Werge
Fernando Racimo
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Fernando Racimo
Kristian Kristiansen
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
3Department of Historical Studies, University of Gothenburg, Gothenburg, Sweden.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Eske Willerslev
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
5GeoGenetics Group, Department of Zoology, University of Cambridge, Cambridge, UK.
101Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
103MARUM, University of Bremen, Bremen, Germany.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Eske Willerslev
  • For correspondence: morten.allentoft@curtin.edu.au martin.sikora@sund.ku.dk ew482@cam.ac.uk
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

Summary

The transitions from foraging to farming and later to pastoralism in Stone Age Eurasia (c. 11-3 thousand years before present, BP) represent some of the most dramatic lifestyle changes in human evolution. We sequenced 317 genomes of primarily Mesolithic and Neolithic individuals from across Eurasia combined with radiocarbon dates, stable isotope data, and pollen records. Genome imputation and co-analysis with previously published shotgun sequencing data resulted in >1600 complete ancient genome sequences offering fine-grained resolution into the Stone Age populations. We observe that: 1) Hunter-gatherer groups were more genetically diverse than previously known, and deeply divergent between western and eastern Eurasia. 2) We identify hitherto genetically undescribed hunter-gatherers from the Middle Don region that contributed ancestry to the later Yamnaya steppe pastoralists; 3) The genetic impact of the Neolithic transition was highly distinct, east and west of a boundary zone extending from the Black Sea to the Baltic. Large-scale shifts in genetic ancestry occurred to the west of this “Great Divide”, including an almost complete replacement of hunter-gatherers in Denmark, while no substantial ancestry shifts took place during the same period to the east. This difference is also reflected in genetic relatedness within the populations, decreasing substantially in the west but not in the east where it remained high until c. 4,000 BP; 4) The second major genetic transformation around 5,000 BP happened at a much faster pace with Steppe-related ancestry reaching most parts of Europe within 1,000-years. Local Neolithic farmers admixed with incoming pastoralists in eastern, western, and southern Europe whereas Scandinavia experienced another near-complete population replacement. Similar dramatic turnover-patterns are evident in western Siberia; 5) Extensive regional differences in the ancestry components involved in these early events remain visible to this day, even within countries. Neolithic farmer ancestry is highest in southern and eastern England while Steppe-related ancestry is highest in the Celtic populations of Scotland, Wales, and Cornwall (this research has been conducted using the UK Biobank resource); 6) Shifts in diet, lifestyle and environment introduced new selection pressures involving at least 21 genomic regions. Most such variants were not universally selected across populations but were only advantageous in particular ancestral backgrounds. Contrary to previous claims, we find that selection on the FADS regions, associated with fatty acid metabolism, began before the Neolithisation of Europe. Similarly, the lactase persistence allele started increasing in frequency before the expansion of Steppe-related groups into Europe and has continued to increase up to the present. Along the genetic cline separating Mesolithic hunter-gatherers from Neolithic farmers, we find significant correlations with trait associations related to skin disorders, diet and lifestyle and mental health status, suggesting marked phenotypic differences between these groups with very different lifestyles. This work provides new insights into major transformations in recent human evolution, elucidating the complex interplay between selection and admixture that shaped patterns of genetic variation in modern populations.

Competing Interest Statement

The authors have declared no competing interest.

Footnotes

  • ↵§ Joint first authors

  • ↵@ Joint last authors

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Back to top
PreviousNext
Posted May 05, 2022.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Population Genomics of Stone Age Eurasia
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Population Genomics of Stone Age Eurasia
Morten E. Allentoft, Martin Sikora, Alba Refoyo-Martínez, Evan K. Irving-Pease, Anders Fischer, William Barrie, Andrés Ingason, Jesper Stenderup, Karl-Göran Sjögren, Alice Pearson, Barbara Mota, Bettina Schulz Paulsson, Alma Halgren, Ruairidh Macleod, Marie Louise Schjellerup Jørkov, Fabrice Demeter, Maria Novosolov, Lasse Sørensen, Poul-Otto Nielsen, Rasmus H.A. Henriksen, Tharsika Vimala, Hugh McColl, Ashot Margaryan, Melissa Ilardo, Andrew Vaughn, Morten Fischer Mortensen, Anne Birgitte Nielsen, Mikkel Ulfeldt Hede, Peter Rasmussen, Lasse Vinner, Gabriel Renaud, Aaron Stern, Theis Zetner Trolle Jensen, Niels Nørkjær Johannsen, Gabriele Scorrano, Hannes Schroeder, Per Lysdahl, Abigail Daisy Ramsøe, Andrei Skorobogatov, Andrew Joseph Schork, Anders Rosengren, Anthony Ruter, Alan Outram, Aleksey A. Timoshenko, Alexandra Buzhilova, Alfredo Coppa, Alisa Zubova, Ana Maria Silva, Anders J. Hansen, Andrey Gromov, Andrey Logvin, Anne Birgitte Gotfredsen, Bjarne Henning Nielsen, Borja González-Rabanal, Carles Lalueza-Fox, Catriona J. McKenzie, Charleen Gaunitz, Concepción Blasco, Corina Liesau, Cristina Martinez-Labarga, Dmitri V. Pozdnyakov, David Cuenca-Solana, David O. Lordkipanidze, Dmitri En’shin, Domingo C. Salazar-García, T. Douglas Price, Dušan Borić, Elena Kostyleva, Elizaveta V. Veselovskaya, Emma R. Usmanova, Enrico Cappellini, Erik Brinch Petersen, Esben Kannegaard, Francesca Radina, Fulya Eylem Yediay, Henri Duday, Igor Gutiérrez-Zugasti, Inna Potekhina, Irina Shevnina, Isin Altinkaya, Jean Guilaine, Jesper Hansen, Joan Emili Aura Tortosa, João Zilhão, Jorge Vega, Kristoffer Buck Pedersen, Krzysztof Tunia, Lei Zhao, Liudmila N. Mylnikova, Lars Larsson, Laure Metz, Levon Yeppiskoposyan, Lisbeth Pedersen, Lucia Sarti, Ludovic Orlando, Ludovic Slimak, Lutz Klassen, Malou Blank, Manuel González-Morales, Mara Silvestrini, Maria Vretemark, Marina S. Nesterova, Marina Rykun, Mario Federico Rolfo, Marzena Szmyt, Marcin Przybyła, Mauro Calattini, Mikhail Sablin, Miluše Dobisíková, Morten Meldgaard, Morten Johansen, Natalia Berezina, Nick Card, Nikolai A. Saveliev, Olga Poshekhonova, Olga Rickards, Olga V. Lozovskaya, Otto Christian Uldum, Paola Aurino, Pavel Kosintsev, Patrice Courtaud, Patricia Ríos, Peder Mortensen, Per Lotz, Per Åke Persson, Pernille Bangsgaard, Peter de Barros Damgaard, Peter Vang Petersen, Pilar Prieto Martinez, Piotr Włodarczak, Roman V. Smolyaninov, Rikke Maring, Roberto Menduiña, Ruben Badalyan, Rune Iversen, Ruslan Turin, Sergey Vasilyiev, Sidsel Wåhlin, Svetlana Borutskaya, Svetlana Skochina, Søren Anker Sørensen, Søren H. Andersen, Thomas Jørgensen, Yuri B. Serikov, Vyacheslav I. Molodin, Vaclav Smrcka, Victor Merz, Vivek Appadurai, Vyacheslav Moiseyev, Yvonne Magnusson, Kurt H. Kjær, Niels Lynnerup, Daniel J. Lawson, Peter H. Sudmant, Simon Rasmussen, Thorfinn Korneliussen, Richard Durbin, Rasmus Nielsen, Olivier Delaneau, Thomas Werge, Fernando Racimo, Kristian Kristiansen, Eske Willerslev
bioRxiv 2022.05.04.490594; doi: https://doi.org/10.1101/2022.05.04.490594
Reddit logo Twitter logo Facebook logo LinkedIn logo Mendeley logo
Citation Tools
Population Genomics of Stone Age Eurasia
Morten E. Allentoft, Martin Sikora, Alba Refoyo-Martínez, Evan K. Irving-Pease, Anders Fischer, William Barrie, Andrés Ingason, Jesper Stenderup, Karl-Göran Sjögren, Alice Pearson, Barbara Mota, Bettina Schulz Paulsson, Alma Halgren, Ruairidh Macleod, Marie Louise Schjellerup Jørkov, Fabrice Demeter, Maria Novosolov, Lasse Sørensen, Poul-Otto Nielsen, Rasmus H.A. Henriksen, Tharsika Vimala, Hugh McColl, Ashot Margaryan, Melissa Ilardo, Andrew Vaughn, Morten Fischer Mortensen, Anne Birgitte Nielsen, Mikkel Ulfeldt Hede, Peter Rasmussen, Lasse Vinner, Gabriel Renaud, Aaron Stern, Theis Zetner Trolle Jensen, Niels Nørkjær Johannsen, Gabriele Scorrano, Hannes Schroeder, Per Lysdahl, Abigail Daisy Ramsøe, Andrei Skorobogatov, Andrew Joseph Schork, Anders Rosengren, Anthony Ruter, Alan Outram, Aleksey A. Timoshenko, Alexandra Buzhilova, Alfredo Coppa, Alisa Zubova, Ana Maria Silva, Anders J. Hansen, Andrey Gromov, Andrey Logvin, Anne Birgitte Gotfredsen, Bjarne Henning Nielsen, Borja González-Rabanal, Carles Lalueza-Fox, Catriona J. McKenzie, Charleen Gaunitz, Concepción Blasco, Corina Liesau, Cristina Martinez-Labarga, Dmitri V. Pozdnyakov, David Cuenca-Solana, David O. Lordkipanidze, Dmitri En’shin, Domingo C. Salazar-García, T. Douglas Price, Dušan Borić, Elena Kostyleva, Elizaveta V. Veselovskaya, Emma R. Usmanova, Enrico Cappellini, Erik Brinch Petersen, Esben Kannegaard, Francesca Radina, Fulya Eylem Yediay, Henri Duday, Igor Gutiérrez-Zugasti, Inna Potekhina, Irina Shevnina, Isin Altinkaya, Jean Guilaine, Jesper Hansen, Joan Emili Aura Tortosa, João Zilhão, Jorge Vega, Kristoffer Buck Pedersen, Krzysztof Tunia, Lei Zhao, Liudmila N. Mylnikova, Lars Larsson, Laure Metz, Levon Yeppiskoposyan, Lisbeth Pedersen, Lucia Sarti, Ludovic Orlando, Ludovic Slimak, Lutz Klassen, Malou Blank, Manuel González-Morales, Mara Silvestrini, Maria Vretemark, Marina S. Nesterova, Marina Rykun, Mario Federico Rolfo, Marzena Szmyt, Marcin Przybyła, Mauro Calattini, Mikhail Sablin, Miluše Dobisíková, Morten Meldgaard, Morten Johansen, Natalia Berezina, Nick Card, Nikolai A. Saveliev, Olga Poshekhonova, Olga Rickards, Olga V. Lozovskaya, Otto Christian Uldum, Paola Aurino, Pavel Kosintsev, Patrice Courtaud, Patricia Ríos, Peder Mortensen, Per Lotz, Per Åke Persson, Pernille Bangsgaard, Peter de Barros Damgaard, Peter Vang Petersen, Pilar Prieto Martinez, Piotr Włodarczak, Roman V. Smolyaninov, Rikke Maring, Roberto Menduiña, Ruben Badalyan, Rune Iversen, Ruslan Turin, Sergey Vasilyiev, Sidsel Wåhlin, Svetlana Borutskaya, Svetlana Skochina, Søren Anker Sørensen, Søren H. Andersen, Thomas Jørgensen, Yuri B. Serikov, Vyacheslav I. Molodin, Vaclav Smrcka, Victor Merz, Vivek Appadurai, Vyacheslav Moiseyev, Yvonne Magnusson, Kurt H. Kjær, Niels Lynnerup, Daniel J. Lawson, Peter H. Sudmant, Simon Rasmussen, Thorfinn Korneliussen, Richard Durbin, Rasmus Nielsen, Olivier Delaneau, Thomas Werge, Fernando Racimo, Kristian Kristiansen, Eske Willerslev
bioRxiv 2022.05.04.490594; doi: https://doi.org/10.1101/2022.05.04.490594

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Evolutionary Biology
Subject Areas
All Articles
  • Animal Behavior and Cognition (4672)
  • Biochemistry (10344)
  • Bioengineering (7658)
  • Bioinformatics (26303)
  • Biophysics (13502)
  • Cancer Biology (10672)
  • Cell Biology (15414)
  • Clinical Trials (138)
  • Developmental Biology (8489)
  • Ecology (12807)
  • Epidemiology (2067)
  • Evolutionary Biology (16835)
  • Genetics (11382)
  • Genomics (15469)
  • Immunology (10603)
  • Microbiology (25186)
  • Molecular Biology (10211)
  • Neuroscience (54385)
  • Paleontology (399)
  • Pathology (1667)
  • Pharmacology and Toxicology (2889)
  • Physiology (4334)
  • Plant Biology (9235)
  • Scientific Communication and Education (1586)
  • Synthetic Biology (2556)
  • Systems Biology (6774)
  • Zoology (1461)