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Glucose-regulated O-GlcNAcylation of DNMT1 inhibits DNA methyltransferase activity and maintenance of genomic methylation
View ORCID ProfileHeon Shin, Amy Leung, Kevin R. Costello, View ORCID ProfileParijat Senapati, Hiroyuki Kato, Dustin E. Schones
doi: https://doi.org/10.1101/2022.05.11.491514
Heon Shin
1Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, California 91010 USA
Amy Leung
1Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, California 91010 USA
Kevin R. Costello
1Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, California 91010 USA
2Irell and Manella Graduate School of Biological Sciences, City of Hope, Duarte, California 91010 USA
Parijat Senapati
1Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, California 91010 USA
Hiroyuki Kato
1Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, California 91010 USA
Dustin E. Schones
1Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, California 91010 USA
2Irell and Manella Graduate School of Biological Sciences, City of Hope, Duarte, California 91010 USA
Posted May 11, 2022.
Glucose-regulated O-GlcNAcylation of DNMT1 inhibits DNA methyltransferase activity and maintenance of genomic methylation
Heon Shin, Amy Leung, Kevin R. Costello, Parijat Senapati, Hiroyuki Kato, Dustin E. Schones
bioRxiv 2022.05.11.491514; doi: https://doi.org/10.1101/2022.05.11.491514
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