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Parallel evolution of mutational fitness effects over 50,000 generations

View ORCID ProfileAnurag Limdi, View ORCID ProfileSiân V. Owen, View ORCID ProfileCristina M. Herren, View ORCID ProfileRichard E. Lenski, View ORCID ProfileMichael Baym
doi: https://doi.org/10.1101/2022.05.17.492023
Anurag Limdi
1Department of Biomedical Informatics and Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
2Molecules, Cells, and Organisms Graduate Program, Harvard University, Cambridge, Massachusetts 02138, USA
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  • ORCID record for Anurag Limdi
Siân V. Owen
1Department of Biomedical Informatics and Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
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Cristina M. Herren
1Department of Biomedical Informatics and Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
3Harvard Data Science Initiative, Harvard University, Boston, Massachusetts 02115, USA
4Department of Marine and Environmental Sciences, Northeastern University, Boston, Massachusetts 02115, USA
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  • ORCID record for Cristina M. Herren
Richard E. Lenski
5Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan 48824, USA
6Ecology, Evolution, and Behavior Program, Michigan State University, East Lansing, Michigan 48824, USA
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Michael Baym
1Department of Biomedical Informatics and Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
3Harvard Data Science Initiative, Harvard University, Boston, Massachusetts 02115, USA
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  • For correspondence: baym@hms.harvard.edu
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Article Information

doi 
https://doi.org/10.1101/2022.05.17.492023
History 
  • March 7, 2023.

Article Versions

  • Version 1 (May 17, 2022 - 21:01).
  • You are viewing Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Anurag Limdi1,2,
  2. Siân V. Owen1,
  3. Cristina M. Herren1,3,4,
  4. Richard E. Lenski5,6 and
  5. Michael Baym1,3,*
  1. 1Department of Biomedical Informatics and Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
  2. 2Molecules, Cells, and Organisms Graduate Program, Harvard University, Cambridge, Massachusetts 02138, USA
  3. 3Harvard Data Science Initiative, Harvard University, Boston, Massachusetts 02115, USA
  4. 4Department of Marine and Environmental Sciences, Northeastern University, Boston, Massachusetts 02115, USA
  5. 5Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan 48824, USA
  6. 6Ecology, Evolution, and Behavior Program, Michigan State University, East Lansing, Michigan 48824, USA
  1. ↵*To whom correspondence should be addressed: baym{at}hms.harvard.edu
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Posted March 07, 2023.
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Parallel evolution of mutational fitness effects over 50,000 generations
Anurag Limdi, Siân V. Owen, Cristina M. Herren, Richard E. Lenski, Michael Baym
bioRxiv 2022.05.17.492023; doi: https://doi.org/10.1101/2022.05.17.492023
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Parallel evolution of mutational fitness effects over 50,000 generations
Anurag Limdi, Siân V. Owen, Cristina M. Herren, Richard E. Lenski, Michael Baym
bioRxiv 2022.05.17.492023; doi: https://doi.org/10.1101/2022.05.17.492023

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