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Metabolic, Fibrotic, and Splicing Pathways Are All Altered in Emery-Dreifuss Muscular Dystrophy Spectrum Patients to Differing Degrees

Jose I. de las Heras, Vanessa Todorow, Lejla Krečinić-Balić, Stefan Hintze, Rafal Czapiewski, Shaun Webb, Benedikt Schoser, Peter Meinke, Eric C. Schirmer
doi: https://doi.org/10.1101/2022.05.20.492778
Jose I. de las Heras
1Institute of Cell Biology, University of Edinburgh, Edinburgh, UK
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Vanessa Todorow
2Friedrich-Baur-Institute, Department of Neurology, LMU Clinic, Ludwig-Maximillians-University, Munich, Germany
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Lejla Krečinić-Balić
2Friedrich-Baur-Institute, Department of Neurology, LMU Clinic, Ludwig-Maximillians-University, Munich, Germany
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Stefan Hintze
2Friedrich-Baur-Institute, Department of Neurology, LMU Clinic, Ludwig-Maximillians-University, Munich, Germany
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Rafal Czapiewski
1Institute of Cell Biology, University of Edinburgh, Edinburgh, UK
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Shaun Webb
3Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK
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Benedikt Schoser
2Friedrich-Baur-Institute, Department of Neurology, LMU Clinic, Ludwig-Maximillians-University, Munich, Germany
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Peter Meinke
2Friedrich-Baur-Institute, Department of Neurology, LMU Clinic, Ludwig-Maximillians-University, Munich, Germany
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  • For correspondence: e.schirmer@ed.ac.uk Peter.Meinke@med.uni-muenchen.de
Eric C. Schirmer
1Institute of Cell Biology, University of Edinburgh, Edinburgh, UK
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  • For correspondence: e.schirmer@ed.ac.uk Peter.Meinke@med.uni-muenchen.de
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Article Information

doi 
https://doi.org/10.1101/2022.05.20.492778
History 
  • May 20, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Jose I. de las Heras1,
  2. Vanessa Todorow2,
  3. Lejla Krečinić-Balić2,
  4. Stefan Hintze2,
  5. Rafal Czapiewski1,
  6. Shaun Webb3,
  7. Benedikt Schoser2,
  8. Peter Meinke2,* and
  9. Eric C. Schirmer1,*
  1. 1Institute of Cell Biology, University of Edinburgh, Edinburgh, UK
  2. 2Friedrich-Baur-Institute, Department of Neurology, LMU Clinic, Ludwig-Maximillians-University, Munich, Germany
  3. 3Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK
  1. ↵*Co-corresponding authors: Eric C. Schirmer Institute of Cell Biology; University of Edinburgh, Kings Buildings; Michael Swann Building, Room 5.22; Max Born Crescent; Edinburgh, EH9 3BF, UK; Phone: +441316507075; E-mail: e.schirmer{at}ed.ac.uk, Peter Meinke, Friedrich-Baur-Institute, Department of Neurology, LMU Clinics, Ludwig-Maximillians-University, Ziemssenstrasse 1, 80336 Munich, Germany; Phone +4989218078279; E-mail: Peter.Meinke{at}med.uni-muenchen.de
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Metabolic, Fibrotic, and Splicing Pathways Are All Altered in Emery-Dreifuss Muscular Dystrophy Spectrum Patients to Differing Degrees
Jose I. de las Heras, Vanessa Todorow, Lejla Krečinić-Balić, Stefan Hintze, Rafal Czapiewski, Shaun Webb, Benedikt Schoser, Peter Meinke, Eric C. Schirmer
bioRxiv 2022.05.20.492778; doi: https://doi.org/10.1101/2022.05.20.492778
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Metabolic, Fibrotic, and Splicing Pathways Are All Altered in Emery-Dreifuss Muscular Dystrophy Spectrum Patients to Differing Degrees
Jose I. de las Heras, Vanessa Todorow, Lejla Krečinić-Balić, Stefan Hintze, Rafal Czapiewski, Shaun Webb, Benedikt Schoser, Peter Meinke, Eric C. Schirmer
bioRxiv 2022.05.20.492778; doi: https://doi.org/10.1101/2022.05.20.492778

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