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Mechanism of treatment-free remission in patients with chronic myeloid leukemia revealed by a computational model of CML evolution

Xiulan Lai, Xiaopei Jiao, Haojian Zhang, Jinzhi Lei
doi: https://doi.org/10.1101/2022.05.20.492875
Xiulan Lai
aInstitute for Mathematical Sciences, Renmin University of China, Beijing, China
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Xiaopei Jiao
bDepartment of Mathematics, Tsinghua University, Beijing, China
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Haojian Zhang
cThe State Key Laboratory Breeding Base of Basic Science of Stomatology-Key Laboratory of Oral Biomedicine, Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China
dFrontier Science Center for Immunology and Metabolism, Medical Research Institute, School of Medicine, Wuhan University, Wuhan, China
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Jinzhi Lei
eSchool of Mathematical Sciences, Center for Applied Mathematics, Tiangong University, Tianjin, China
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  • For correspondence: jzlei@tiangong.edu.cn
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Article Information

doi 
https://doi.org/10.1101/2022.05.20.492875
History 
  • May 21, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Xiulan Laia,1,
  2. Xiaopei Jiaob,1,
  3. Haojian Zhangc,d and
  4. Jinzhi Leie,*
  1. aInstitute for Mathematical Sciences, Renmin University of China, Beijing, China
  2. bDepartment of Mathematics, Tsinghua University, Beijing, China
  3. cThe State Key Laboratory Breeding Base of Basic Science of Stomatology-Key Laboratory of Oral Biomedicine, Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China
  4. dFrontier Science Center for Immunology and Metabolism, Medical Research Institute, School of Medicine, Wuhan University, Wuhan, China
  5. eSchool of Mathematical Sciences, Center for Applied Mathematics, Tiangong University, Tianjin, China
  1. ↵*Corresponding author Email address: jzlei{at}tiangong.edu.cn (Jinzhi Lei)
  1. ↵1 These authors contributed equally to this work.

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Posted May 21, 2022.
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Mechanism of treatment-free remission in patients with chronic myeloid leukemia revealed by a computational model of CML evolution
Xiulan Lai, Xiaopei Jiao, Haojian Zhang, Jinzhi Lei
bioRxiv 2022.05.20.492875; doi: https://doi.org/10.1101/2022.05.20.492875
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Mechanism of treatment-free remission in patients with chronic myeloid leukemia revealed by a computational model of CML evolution
Xiulan Lai, Xiaopei Jiao, Haojian Zhang, Jinzhi Lei
bioRxiv 2022.05.20.492875; doi: https://doi.org/10.1101/2022.05.20.492875

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