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Within-host genotypic and phenotypic diversity of contemporaneous carbapenem-resistant Klebsiella pneumoniae from blood cultures of patients with bacteremia

Shaoji Cheng, Giuseppe Fleres, View ORCID ProfileLiang Chen, Guojun Liu, Binghua Hao, Anthony Newbrough, Eileen Driscoll, View ORCID ProfileRyan K. Shields, Kevin M. Squires, Ting-yu Chu, View ORCID ProfileBarry N. Kreiswirth, M. Hong Nguyen, Cornelius J. Clancy
doi: https://doi.org/10.1101/2022.05.26.493675
Shaoji Cheng
1University of Pittsburgh, Pittsburgh, PA
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Giuseppe Fleres
1University of Pittsburgh, Pittsburgh, PA
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Liang Chen
2Hackensack Meridian School of Medicine & Hackensack Meridian Health Center for Discovery and Innovation, Nutley, NJ
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  • ORCID record for Liang Chen
Guojun Liu
1University of Pittsburgh, Pittsburgh, PA
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Binghua Hao
3University of Pittsburgh Medical Center, Pittsburgh, PA
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Anthony Newbrough
1University of Pittsburgh, Pittsburgh, PA
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Eileen Driscoll
1University of Pittsburgh, Pittsburgh, PA
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Ryan K. Shields
1University of Pittsburgh, Pittsburgh, PA
3University of Pittsburgh Medical Center, Pittsburgh, PA
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  • ORCID record for Ryan K. Shields
Kevin M. Squires
1University of Pittsburgh, Pittsburgh, PA
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Ting-yu Chu
2Hackensack Meridian School of Medicine & Hackensack Meridian Health Center for Discovery and Innovation, Nutley, NJ
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Barry N. Kreiswirth
2Hackensack Meridian School of Medicine & Hackensack Meridian Health Center for Discovery and Innovation, Nutley, NJ
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  • ORCID record for Barry N. Kreiswirth
M. Hong Nguyen
1University of Pittsburgh, Pittsburgh, PA
3University of Pittsburgh Medical Center, Pittsburgh, PA
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  • For correspondence: mhn5@pitt.edu
Cornelius J. Clancy
1University of Pittsburgh, Pittsburgh, PA
4VA Pittsburgh Healthcare System, Pittsburgh, PA
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Article Information

doi 
https://doi.org/10.1101/2022.05.26.493675
History 
  • May 27, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Shaoji Cheng1,
  2. Giuseppe Fleres1,
  3. Liang Chen2,
  4. Guojun Liu1,
  5. Binghua Hao3,
  6. Anthony Newbrough1,
  7. Eileen Driscoll1,
  8. Ryan K. Shields1,3,
  9. Kevin M. Squires1,
  10. Ting-yu Chu2,
  11. Barry N. Kreiswirth2,
  12. M. Hong Nguyen1,3,*,† and
  13. Cornelius J. Clancy1,4,*
  1. 1University of Pittsburgh, Pittsburgh, PA
  2. 2Hackensack Meridian School of Medicine & Hackensack Meridian Health Center for Discovery and Innovation, Nutley, NJ
  3. 3University of Pittsburgh Medical Center, Pittsburgh, PA
  4. 4VA Pittsburgh Healthcare System, Pittsburgh, PA
  1. ↵†Corresponding author: M. Hong Nguyen University of Pittsburgh 3550 Terrace Street Suite 871, Pittsburgh, PA 15261, Phone: (412) 383-5193, Email: mhn5{at}pitt.edu
  1. ↵* MHN and CJC contributed equally to this paper

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Posted May 27, 2022.
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Within-host genotypic and phenotypic diversity of contemporaneous carbapenem-resistant Klebsiella pneumoniae from blood cultures of patients with bacteremia
Shaoji Cheng, Giuseppe Fleres, Liang Chen, Guojun Liu, Binghua Hao, Anthony Newbrough, Eileen Driscoll, Ryan K. Shields, Kevin M. Squires, Ting-yu Chu, Barry N. Kreiswirth, M. Hong Nguyen, Cornelius J. Clancy
bioRxiv 2022.05.26.493675; doi: https://doi.org/10.1101/2022.05.26.493675
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Within-host genotypic and phenotypic diversity of contemporaneous carbapenem-resistant Klebsiella pneumoniae from blood cultures of patients with bacteremia
Shaoji Cheng, Giuseppe Fleres, Liang Chen, Guojun Liu, Binghua Hao, Anthony Newbrough, Eileen Driscoll, Ryan K. Shields, Kevin M. Squires, Ting-yu Chu, Barry N. Kreiswirth, M. Hong Nguyen, Cornelius J. Clancy
bioRxiv 2022.05.26.493675; doi: https://doi.org/10.1101/2022.05.26.493675

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