A single cell spatial temporal atlas of skeletal muscle reveals cellular neighborhoods that orchestrate regeneration and become disrupted in aging

Yu Xin Wang; Colin A. Holbrook; James N. Hamilton; Jasmin Garoussian; Mohsen Afshar; Shiqi Su; Christian M. Schürch; Michael Y. Lee; Yury Goltsev; Anshul Kundaje; Garry P. Nolan; Helen M. Blau

doi:10.1101/2022.06.10.494732

New Results

A single cell spatial temporal atlas of skeletal muscle reveals cellular neighborhoods that orchestrate regeneration and become disrupted in aging

View ORCID ProfileYu Xin Wang, Colin A. Holbrook, James N. Hamilton, Jasmin Garoussian, Mohsen Afshar, Shiqi Su, Christian M. Schürch, Michael Y. Lee, Yury Goltsev, Anshul Kundaje, Garry P. Nolan, Helen M. Blau

doi: https://doi.org/10.1101/2022.06.10.494732

Yu Xin Wang

1Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Yu Xin Wang

Colin A. Holbrook

1Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

James N. Hamilton

1Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jasmin Garoussian

1Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, USA

2Institute of Sports Medicine Copenhagen, Department of Orthopedic Surgery, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark

3Center for Healthy Aging, Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Mohsen Afshar

1Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Shiqi Su

1Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Christian M. Schürch

1Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, USA

4Department of Pathology, Stanford University School of Medicine, Stanford, USA

5Department of Pathology and Neuropathology, University Hospital and Comprehensive Cancer Center Tübingen, Tübingen, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Michael Y. Lee

1Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, USA

4Department of Pathology, Stanford University School of Medicine, Stanford, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yury Goltsev

1Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, USA

4Department of Pathology, Stanford University School of Medicine, Stanford, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Anshul Kundaje

6Department of Genetics, Stanford University, Stanford, USA

7Department of Computer Science, Stanford University, Stanford, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Garry P. Nolan

4Department of Pathology, Stanford University School of Medicine, Stanford, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Helen M. Blau

1Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: [email protected]

Abstract
Full Text
Info/History
Metrics
Supplementary material
Preview PDF

Article usage

Article usage: June 2022 to February 2025

	Abstract	Full	Pdf
Jun 2022	2121	193	914
Jul 2022	379	62	173
Aug 2022	289	78	126
Sep 2022	229	54	90
Oct 2022	190	45	78
Nov 2022	189	78	131
Dec 2022	176	59	79
Jan 2023	219	53	95
Feb 2023	136	90	87
Mar 2023	186	111	125
Apr 2023	155	87	121
May 2023	133	103	89
Jun 2023	182	117	128
Jul 2023	157	86	111
Aug 2023	150	111	103
Sep 2023	133	87	67
Oct 2023	237	80	103
Nov 2023	155	87	75
Dec 2023	81	36	40
Jan 2024	146	51	58
Feb 2024	131	56	43
Mar 2024	98	37	55
Apr 2024	94	37	69
May 2024	122	87	59
Jun 2024	103	44	52
Jul 2024	98	42	37
Aug 2024	88	32	170
Sep 2024	76	52	29
Oct 2024	74	56	39
Nov 2024	96	58	49
Dec 2024	99	41	35
Jan 2025	106	46	41
Feb 2025	41	17	19

View the discussion thread.

PreviousNext

Posted June 10, 2022.

Download PDF

Supplementary Material

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following A single cell spatial temporal atlas of skeletal muscle reveals cellular neighborhoods that orchestrate regeneration and become disrupted in aging

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

A single cell spatial temporal atlas of skeletal muscle reveals cellular neighborhoods that orchestrate regeneration and become disrupted in aging

Yu Xin Wang, Colin A. Holbrook, James N. Hamilton, Jasmin Garoussian, Mohsen Afshar, Shiqi Su, Christian M. Schürch, Michael Y. Lee, Yury Goltsev, Anshul Kundaje, Garry P. Nolan, Helen M. Blau

bioRxiv 2022.06.10.494732; doi: https://doi.org/10.1101/2022.06.10.494732

Share This Article:

Citation Tools

A single cell spatial temporal atlas of skeletal muscle reveals cellular neighborhoods that orchestrate regeneration and become disrupted in aging

Yu Xin Wang, Colin A. Holbrook, James N. Hamilton, Jasmin Garoussian, Mohsen Afshar, Shiqi Su, Christian M. Schürch, Michael Y. Lee, Yury Goltsev, Anshul Kundaje, Garry P. Nolan, Helen M. Blau

bioRxiv 2022.06.10.494732; doi: https://doi.org/10.1101/2022.06.10.494732

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Cell Biology

Subject Areas

All Articles

Animal Behavior and Cognition (6111)
Biochemistry (13924)
Bioengineering (10604)
Bioinformatics (33730)
Biophysics (17365)
Cancer Biology (14451)
Cell Biology (20441)
Clinical Trials (138)
Developmental Biology (11014)
Ecology (16257)
Epidemiology (2067)
Evolutionary Biology (20569)
Genetics (13538)
Genomics (18851)
Immunology (13985)
Microbiology (32634)
Molecular Biology (13585)
Neuroscience (71128)
Paleontology (533)
Pathology (2228)
Pharmacology and Toxicology (3788)
Physiology (5979)
Plant Biology (12185)
Scientific Communication and Education (1827)
Synthetic Biology (3410)
Systems Biology (8265)
Zoology (1879)