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Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry
Lalita Priyamvada, Wouter W. Kallemeijn, Monica Faronato, Kimberly Wilkins, Cynthia S. Goldsmith, Catherine A. Cotter, Suany Ojeda, Roberto Solari, Bernard Moss, View ORCID ProfileEdward W. Tate, View ORCID ProfilePanayampalli Subbian Satheshkumar
doi: https://doi.org/10.1101/2022.06.13.495866
Lalita Priyamvada
1Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, GA 30329. USA
Wouter W. Kallemeijn
2Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK
3The Francis Crick Institute, 1 Midland Road, London NW1 1AT, United Kingdom
Monica Faronato
2Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK
3The Francis Crick Institute, 1 Midland Road, London NW1 1AT, United Kingdom
Kimberly Wilkins
1Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, GA 30329. USA
Cynthia S. Goldsmith
4Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, GA 30329. USA
Catherine A. Cotter
5Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Suany Ojeda
5Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Roberto Solari
6National Heart and Lung Institute, Imperial College of Science, Technology & Medicine, London W2 1PG, UK
Bernard Moss
5Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Edward W. Tate
2Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK
3The Francis Crick Institute, 1 Midland Road, London NW1 1AT, United Kingdom
Panayampalli Subbian Satheshkumar
1Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, GA 30329. USA
Article usage
Posted June 13, 2022.
Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry
Lalita Priyamvada, Wouter W. Kallemeijn, Monica Faronato, Kimberly Wilkins, Cynthia S. Goldsmith, Catherine A. Cotter, Suany Ojeda, Roberto Solari, Bernard Moss, Edward W. Tate, Panayampalli Subbian Satheshkumar
bioRxiv 2022.06.13.495866; doi: https://doi.org/10.1101/2022.06.13.495866
Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry
Lalita Priyamvada, Wouter W. Kallemeijn, Monica Faronato, Kimberly Wilkins, Cynthia S. Goldsmith, Catherine A. Cotter, Suany Ojeda, Roberto Solari, Bernard Moss, Edward W. Tate, Panayampalli Subbian Satheshkumar
bioRxiv 2022.06.13.495866; doi: https://doi.org/10.1101/2022.06.13.495866
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