Single locus phosphoproteomics reveals phosphorylation of RPA-1 is required for generation of single-strand DNA following a break at a subtelomeric locus

Emilia McLaughlin; Annick Dujeancourt-Henry; Thibault Chaze; Quentin Giai Gianetto; Mariette Matondo; Michael D Urbaniak; Lucy Glover

doi:10.1101/2022.06.15.496243

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Single locus phosphoproteomics reveals phosphorylation of RPA-1 is required for generation of single-strand DNA following a break at a subtelomeric locus

Emilia McLaughlin, Annick Dujeancourt-Henry, Thibault Chaze, Quentin Giai Gianetto, Mariette Matondo, View ORCID ProfileMichael D Urbaniak, Lucy Glover

doi: https://doi.org/10.1101/2022.06.15.496243

Emilia McLaughlin

1Institut Pasteur, Université Paris Cité, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, F-75015, Paris, France

2Sorbonne Université, Collège doctoral, F-75005 Paris, France

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Annick Dujeancourt-Henry

1Institut Pasteur, Université Paris Cité, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, F-75015, Paris, France

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Thibault Chaze

3Institut Pasteur, Université Paris Cité, Proteomics Platform, Mass Spectrometry for Biology Unit, Centre National de la Recherche Scientifique, UAR 2024, 75015 Paris, France

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Quentin Giai Gianetto

3Institut Pasteur, Université Paris Cité, Proteomics Platform, Mass Spectrometry for Biology Unit, Centre National de la Recherche Scientifique, UAR 2024, 75015 Paris, France

4Institut Pasteur, Université Paris Cité, Bioinformatics and Biostatistics HUB, 75015 Paris, France

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Mariette Matondo

3Institut Pasteur, Université Paris Cité, Proteomics Platform, Mass Spectrometry for Biology Unit, Centre National de la Recherche Scientifique, UAR 2024, 75015 Paris, France

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Michael D Urbaniak

5Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster, UK

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ORCID record for Michael D Urbaniak

Lucy Glover

1Institut Pasteur, Université Paris Cité, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, F-75015, Paris, France

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For correspondence: lucy.glover@pasteur.fr

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Single locus phosphoproteomics reveals phosphorylation of RPA-1 is required for generation of single-strand DNA following a break at a subtelomeric locus

Emilia McLaughlin, Annick Dujeancourt-Henry, Thibault Chaze, Quentin Giai Gianetto, Mariette Matondo, Michael D Urbaniak, Lucy Glover

bioRxiv 2022.06.15.496243; doi: https://doi.org/10.1101/2022.06.15.496243

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Single locus phosphoproteomics reveals phosphorylation of RPA-1 is required for generation of single-strand DNA following a break at a subtelomeric locus

Emilia McLaughlin, Annick Dujeancourt-Henry, Thibault Chaze, Quentin Giai Gianetto, Mariette Matondo, Michael D Urbaniak, Lucy Glover

bioRxiv 2022.06.15.496243; doi: https://doi.org/10.1101/2022.06.15.496243

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