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Development of a new DHFR-based destabilizing domain with enhanced basal turnover and applicability in mammalian systems
Emi Nakahara, Vishruth Mullapudi, Lukasz A. Joachimiak, View ORCID ProfileJohn D. Hulleman
doi: https://doi.org/10.1101/2022.06.21.495152
Emi Nakahara
1Department of Ophthalmology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas, 75390, United States
Vishruth Mullapudi
2Center for Alzheimer’s and Neurodegenerative Diseases, O’Donnell Brain Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas, 75390, United States
Lukasz A. Joachimiak
2Center for Alzheimer’s and Neurodegenerative Diseases, O’Donnell Brain Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas, 75390, United States
3Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas, 75390, United States
John D. Hulleman
1Department of Ophthalmology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas, 75390, United States
4Department of Pharmacology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas, 75390, United States
Posted June 21, 2022.
Development of a new DHFR-based destabilizing domain with enhanced basal turnover and applicability in mammalian systems
Emi Nakahara, Vishruth Mullapudi, Lukasz A. Joachimiak, John D. Hulleman
bioRxiv 2022.06.21.495152; doi: https://doi.org/10.1101/2022.06.21.495152
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