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In Vitro Evaluation and Mitigation of Niclosamide’s Liabilities as a COVID-19 Treatment
View ORCID ProfileJesse W. Wotring, View ORCID ProfileSean M. McCarty, View ORCID ProfileKhadija Shafiq, View ORCID ProfileCharles J. Zhang, Theophilus Nguyen, View ORCID ProfileSophia R. Meyer, View ORCID ProfileReid Fursmidt, View ORCID ProfileCarmen Mirabelli, View ORCID ProfileMartin C. Clasby, View ORCID ProfileChristiane E. Wobus, View ORCID ProfileMatthew J. O’Meara, View ORCID ProfileJonathan Z. Sexton
doi: https://doi.org/10.1101/2022.06.24.497526
Jesse W. Wotring
1Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA
Sean M. McCarty
1Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA
Khadija Shafiq
1Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA
Charles J. Zhang
1Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA
Theophilus Nguyen
2Department of Internal Medicine, Gastroenterology and Hepatology, Michigan Medicine at the University of Michigan, Ann Arbor, MI, 48109, USA
Sophia R. Meyer
1Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA
Reid Fursmidt
2Department of Internal Medicine, Gastroenterology and Hepatology, Michigan Medicine at the University of Michigan, Ann Arbor, MI, 48109, USA
Carmen Mirabelli
3Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA
Martin C. Clasby
1Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA
Christiane E. Wobus
3Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA
Matthew J. O’Meara
4Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA
Jonathan Z. Sexton
1Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA
2Department of Internal Medicine, Gastroenterology and Hepatology, Michigan Medicine at the University of Michigan, Ann Arbor, MI, 48109, USA
5U-M Center for Drug Repurposing, University of Michigan, Ann Arbor, MI, 48109, USA
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Posted June 24, 2022.
In Vitro Evaluation and Mitigation of Niclosamide’s Liabilities as a COVID-19 Treatment
Jesse W. Wotring, Sean M. McCarty, Khadija Shafiq, Charles J. Zhang, Theophilus Nguyen, Sophia R. Meyer, Reid Fursmidt, Carmen Mirabelli, Martin C. Clasby, Christiane E. Wobus, Matthew J. O’Meara, Jonathan Z. Sexton
bioRxiv 2022.06.24.497526; doi: https://doi.org/10.1101/2022.06.24.497526
In Vitro Evaluation and Mitigation of Niclosamide’s Liabilities as a COVID-19 Treatment
Jesse W. Wotring, Sean M. McCarty, Khadija Shafiq, Charles J. Zhang, Theophilus Nguyen, Sophia R. Meyer, Reid Fursmidt, Carmen Mirabelli, Martin C. Clasby, Christiane E. Wobus, Matthew J. O’Meara, Jonathan Z. Sexton
bioRxiv 2022.06.24.497526; doi: https://doi.org/10.1101/2022.06.24.497526
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