Single-nucleus resolution mapping of the adult C. elegans and its application to elucidate inter- and trans-generational response to alcohol

Lisa Truong; Yen-Wei Chen; Rio Barrere-Cain; Karissa Shuck; Wen Xiao; Max T. Levenson; Eduardo da Veiga Beltrame; Blake Panter; Ella Reich; Paul W. Sternberg; Xia Yang; Patrick Allard

doi:10.1101/2022.07.21.500524

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Single-nucleus resolution mapping of the adult C. elegans and its application to elucidate inter- and trans-generational response to alcohol

Lisa Truong, Yen-Wei Chen, Rio Barrere-Cain, Karissa Shuck, Wen Xiao, Max T. Levenson, Eduardo da Veiga Beltrame, Blake Panter, Ella Reich, View ORCID ProfilePaul W. Sternberg, Xia Yang, View ORCID ProfilePatrick Allard

doi: https://doi.org/10.1101/2022.07.21.500524

Lisa Truong

2Human Genetics Graduate Program, UCLA, Los Angeles, CA. 90095

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Yen-Wei Chen

3Molecular Toxicology Inter-Departmental Program, UCLA, Los Angeles, CA. 90095

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Rio Barrere-Cain

4Institute for Society & Genetics, UCLA, Los Angeles, CA. 90095

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Karissa Shuck

4Institute for Society & Genetics, UCLA, Los Angeles, CA. 90095

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Wen Xiao

5Department of Microbiology, Immunology, and Molecular Genetics, UCLA, Los Angeles, CA. 90095

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Max T. Levenson

3Molecular Toxicology Inter-Departmental Program, UCLA, Los Angeles, CA. 90095

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Eduardo da Veiga Beltrame

6Biology and Biological Engineering, California Institute of Technology, Pasadena, CA. 91125

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Blake Panter

4Institute for Society & Genetics, UCLA, Los Angeles, CA. 90095

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Ella Reich

4Institute for Society & Genetics, UCLA, Los Angeles, CA. 90095

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Paul W. Sternberg

6Biology and Biological Engineering, California Institute of Technology, Pasadena, CA. 91125

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ORCID record for Paul W. Sternberg

Xia Yang

7Integrative Biology and Physiology Department, UCLA, Los Angeles, CA. 90095

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Patrick Allard

3Molecular Toxicology Inter-Departmental Program, UCLA, Los Angeles, CA. 90095

4Institute for Society & Genetics, UCLA, Los Angeles, CA. 90095

8Molecular Biology Institute, UCLA, Los Angeles, CA. 90095

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ORCID record for Patrick Allard
For correspondence: pallard@ucla.edu

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Supplemental Information[supplements/500524_file04.docx]
Supplemental File 1_Dashboard[supplements/500524_file05.pdf]
Table S1 smFISH probes[supplements/500524_file06.xlsx]
Table S2 DEG_F1_0.05[supplements/500524_file07.xlsx]
Table S3 DEG_F1_0.50[supplements/500524_file08.xlsx]
Table S4 Pathway analysis[supplements/500524_file09.csv]
Table S5 DEG_F3_0.05[supplements/500524_file10.xlsx]
Table S6 DEG_F3_0.50[supplements/500524_file11.xlsx]

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Posted July 22, 2022.

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Single-nucleus resolution mapping of the adult C. elegans and its application to elucidate inter- and trans-generational response to alcohol

Lisa Truong, Yen-Wei Chen, Rio Barrere-Cain, Karissa Shuck, Wen Xiao, Max T. Levenson, Eduardo da Veiga Beltrame, Blake Panter, Ella Reich, Paul W. Sternberg, Xia Yang, Patrick Allard

bioRxiv 2022.07.21.500524; doi: https://doi.org/10.1101/2022.07.21.500524

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Single-nucleus resolution mapping of the adult C. elegans and its application to elucidate inter- and trans-generational response to alcohol

Lisa Truong, Yen-Wei Chen, Rio Barrere-Cain, Karissa Shuck, Wen Xiao, Max T. Levenson, Eduardo da Veiga Beltrame, Blake Panter, Ella Reich, Paul W. Sternberg, Xia Yang, Patrick Allard

bioRxiv 2022.07.21.500524; doi: https://doi.org/10.1101/2022.07.21.500524

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