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Cloud-controlled microscopy enables remote project-based biology education in Latinx communities in the United States and Latin America

View ORCID ProfilePierre V. Baudin, View ORCID ProfileRaina E. Sacksteder, View ORCID ProfileAtesh K. Worthington, View ORCID ProfileKateryna Voitiuk, View ORCID ProfileVictoria T. Ly, Ryan N. Hoffman, View ORCID ProfileMatthew A.T. Elliott, View ORCID ProfileDavid F. Parks, Rebecca Ward, View ORCID ProfileSebastian Torres-Montoya, Finn Amend, View ORCID ProfileNatalia Montellano Duran, Paola A. Vargas, Guadalupe Martinez, Lucia Elena Alvarado-Arnez, View ORCID ProfileDrew Ehrlich, View ORCID ProfileYohei M. Rosen, View ORCID ProfileArnar Breevoort, View ORCID ProfileTallulah Schouten, View ORCID ProfileSri Kurniawan, View ORCID ProfileDavid Haussler, View ORCID ProfileMircea Teodorescu, View ORCID ProfileMohammed A. Mostajo-Radji
doi: https://doi.org/10.1101/2022.08.05.502091
Pierre V. Baudin
aDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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  • ORCID record for Pierre V. Baudin
Raina E. Sacksteder
cDepartment of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Atesh K. Worthington
dDepartment of Molecular, Cellular and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
eInstitute for the Biology of Stem Cells, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Kateryna Voitiuk
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
fDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Victoria T. Ly
aDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Ryan N. Hoffman
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
dDepartment of Molecular, Cellular and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Matthew A.T. Elliott
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
fDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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David F. Parks
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
fDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Rebecca Ward
gAlisal High School, Alisal High School, Salinas, CA, 93905, USA
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Sebastian Torres-Montoya
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
fDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Finn Amend
aDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Natalia Montellano Duran
hBiotechnology, Universidad Catolica Boliviana San Pablo, Santa Cruz de la Sierra, Bolivia
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  • ORCID record for Natalia Montellano Duran
Paola A. Vargas
hBiotechnology, Universidad Catolica Boliviana San Pablo, Santa Cruz de la Sierra, Bolivia
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Guadalupe Martinez
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Lucia Elena Alvarado-Arnez
iNational Research Coordination, Franz Tamayo University, La Paz, Bolivia
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Drew Ehrlich
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
jDepartment of Computational Media, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Yohei M. Rosen
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
dDepartment of Molecular, Cellular and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Arnar Breevoort
kDepartment of Neurology, University of California San Francisco, San Francisco, CA, 94158, USA
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Tallulah Schouten
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
dDepartment of Molecular, Cellular and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Sri Kurniawan
jDepartment of Computational Media, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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David Haussler
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
fDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
lHoward Hughes Medical Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Mircea Teodorescu
aDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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Mohammed A. Mostajo-Radji
bGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA
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  • ORCID record for Mohammed A. Mostajo-Radji
  • For correspondence: mmostajo@ucsc.edu
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Abstract

Project-based learning (PBL) has long been recognized as an effective way to teach complex biology concepts. However, not all institutions have the resources to facilitate effective project-based coursework for students. We have developed a framework for facilitating PBL using remote-controlled internet-connected microscopes. Through this approach, one lab facility can host an experiment allowing simultaneous interaction by many students worldwide. Experiments on this platform can be run on long timescales and with materials that are typically unavailable to high school classrooms. This allows students to perform novel research projects rather than just repeat standard classroom experiments. To investigate the impact of this program, we designed and ran six user studies with students worldwide. All experiments were executed in Santa Cruz and San Francisco, California, with observations and decisions made remotely by the students using their personal computers and cellphones. In surveys gathered after the experiments’ conclusion, students reported increased excitement for science and a greater desire to pursue a career in STEM. This framework represents a novel, scalable, and effective PBL approach that has the potential to democratize biology and STEM education around the world.

Competing Interest Statement

P.V.B., K.V., V.T.L., Y.M.R., D.H. and M.T. have submitted patent applications related to Internet-of-Things-enabled microscopy. M.A.M.-R. is a cofounder of Paika, a company for remote people-to-people interactions. The authors declare no other conflicts of interests.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.
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Posted August 11, 2022.
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Cloud-controlled microscopy enables remote project-based biology education in Latinx communities in the United States and Latin America
Pierre V. Baudin, Raina E. Sacksteder, Atesh K. Worthington, Kateryna Voitiuk, Victoria T. Ly, Ryan N. Hoffman, Matthew A.T. Elliott, David F. Parks, Rebecca Ward, Sebastian Torres-Montoya, Finn Amend, Natalia Montellano Duran, Paola A. Vargas, Guadalupe Martinez, Lucia Elena Alvarado-Arnez, Drew Ehrlich, Yohei M. Rosen, Arnar Breevoort, Tallulah Schouten, Sri Kurniawan, David Haussler, Mircea Teodorescu, Mohammed A. Mostajo-Radji
bioRxiv 2022.08.05.502091; doi: https://doi.org/10.1101/2022.08.05.502091
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Cloud-controlled microscopy enables remote project-based biology education in Latinx communities in the United States and Latin America
Pierre V. Baudin, Raina E. Sacksteder, Atesh K. Worthington, Kateryna Voitiuk, Victoria T. Ly, Ryan N. Hoffman, Matthew A.T. Elliott, David F. Parks, Rebecca Ward, Sebastian Torres-Montoya, Finn Amend, Natalia Montellano Duran, Paola A. Vargas, Guadalupe Martinez, Lucia Elena Alvarado-Arnez, Drew Ehrlich, Yohei M. Rosen, Arnar Breevoort, Tallulah Schouten, Sri Kurniawan, David Haussler, Mircea Teodorescu, Mohammed A. Mostajo-Radji
bioRxiv 2022.08.05.502091; doi: https://doi.org/10.1101/2022.08.05.502091

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