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The logical structure of experiments lays the foundation for a theory of reproducibility

Erkan O. Buzbas, View ORCID ProfileBerna Devezer, View ORCID ProfileBert Baumgaertner
doi: https://doi.org/10.1101/2022.08.10.503444
Erkan O. Buzbas
1Department of Mathematics and Statistical Science, University of Idaho
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  • For correspondence: erkanb@uidaho.edu
Berna Devezer
1Department of Mathematics and Statistical Science, University of Idaho
2Department of Business, University of Idaho
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Bert Baumgaertner
3Department of Politics and Philosophy, University of Idaho
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Abstract

The scientific reform movement has proposed openness as a potential remedy to the putative reproducibility or replication crisis. However, the conceptual relationship between openness, replication experiments, and results reproducibility has been obscure. We analyze the logical structure of experiments, define the mathematical notion of idealized experiment, and use this notion to advance a theory of reproducibility. Idealized experiments clearly delineate the concepts of replication and results reproducibility, and capture key differences with precision, allowing us to study the relationship among them. We show how results reproducibility varies as a function of: the elements of an idealized experiment, the true data generating mechanism, and the closeness of the replication experiment to an original experiment. We clarify how openness of experiments is related to designing informative replication experiments and to obtaining reproducible results. With formal backing and evidence, we argue that the current “crisis” reflects inadequate attention to a theoretical understanding of results reproducibility.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
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Posted August 12, 2022.
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The logical structure of experiments lays the foundation for a theory of reproducibility
Erkan O. Buzbas, Berna Devezer, Bert Baumgaertner
bioRxiv 2022.08.10.503444; doi: https://doi.org/10.1101/2022.08.10.503444
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The logical structure of experiments lays the foundation for a theory of reproducibility
Erkan O. Buzbas, Berna Devezer, Bert Baumgaertner
bioRxiv 2022.08.10.503444; doi: https://doi.org/10.1101/2022.08.10.503444

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