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Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
View ORCID ProfileGiorgio Gaglia, View ORCID ProfileMegan L. Burger, View ORCID ProfileCecily C. Ritch, View ORCID ProfileDanae Rammos, Yang Dai, View ORCID ProfileGrace E. Crossland, View ORCID ProfileSara Z. Tavana, View ORCID ProfileSimon Warchol, View ORCID ProfileAlex M. Jaeger, Santiago Naranjo, View ORCID ProfileShannon Coy, View ORCID ProfileAjit J. Nirmal, View ORCID ProfileRobert Krueger, View ORCID ProfileJia-Ren Lin, View ORCID ProfileHanspeter Pfister, View ORCID ProfilePeter K Sorger, View ORCID ProfileTyler Jacks, View ORCID ProfileSandro Santagata
doi: https://doi.org/10.1101/2022.08.11.503237
Giorgio Gaglia
1Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, 02115, USA
2Ludwig Center at Harvard, Harvard Medical School, Boston, MA 02115, USA
3Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
Megan L. Burger
4David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
5Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Cecily C. Ritch
1Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, 02115, USA
2Ludwig Center at Harvard, Harvard Medical School, Boston, MA 02115, USA
3Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
Danae Rammos
1Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, 02115, USA
2Ludwig Center at Harvard, Harvard Medical School, Boston, MA 02115, USA
3Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
Yang Dai
1Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, 02115, USA
2Ludwig Center at Harvard, Harvard Medical School, Boston, MA 02115, USA
3Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
Grace E. Crossland
4David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Sara Z. Tavana
4David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Simon Warchol
6School of Engineering and Applied Sciences, Harvard University, Boston, MA 02134, USA
Alex M. Jaeger
4David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Santiago Naranjo
4David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
5Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Shannon Coy
1Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, 02115, USA
2Ludwig Center at Harvard, Harvard Medical School, Boston, MA 02115, USA
3Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
Ajit J. Nirmal
1Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, 02115, USA
7Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA
Robert Krueger
1Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, 02115, USA
6School of Engineering and Applied Sciences, Harvard University, Boston, MA 02134, USA
Jia-Ren Lin
1Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, 02115, USA
2Ludwig Center at Harvard, Harvard Medical School, Boston, MA 02115, USA
Hanspeter Pfister
6School of Engineering and Applied Sciences, Harvard University, Boston, MA 02134, USA
Peter K Sorger
1Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, 02115, USA
2Ludwig Center at Harvard, Harvard Medical School, Boston, MA 02115, USA
8Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA
Tyler Jacks
4David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
5Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Sandro Santagata
1Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, 02115, USA
2Ludwig Center at Harvard, Harvard Medical School, Boston, MA 02115, USA
3Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
8Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA
Article usage
Posted August 13, 2022.
Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
Giorgio Gaglia, Megan L. Burger, Cecily C. Ritch, Danae Rammos, Yang Dai, Grace E. Crossland, Sara Z. Tavana, Simon Warchol, Alex M. Jaeger, Santiago Naranjo, Shannon Coy, Ajit J. Nirmal, Robert Krueger, Jia-Ren Lin, Hanspeter Pfister, Peter K Sorger, Tyler Jacks, Sandro Santagata
bioRxiv 2022.08.11.503237; doi: https://doi.org/10.1101/2022.08.11.503237
Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
Giorgio Gaglia, Megan L. Burger, Cecily C. Ritch, Danae Rammos, Yang Dai, Grace E. Crossland, Sara Z. Tavana, Simon Warchol, Alex M. Jaeger, Santiago Naranjo, Shannon Coy, Ajit J. Nirmal, Robert Krueger, Jia-Ren Lin, Hanspeter Pfister, Peter K Sorger, Tyler Jacks, Sandro Santagata
bioRxiv 2022.08.11.503237; doi: https://doi.org/10.1101/2022.08.11.503237
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