New Results
Combined loss of obscurin and obscurin-like 1 in murine hearts results in diastolic dysfunction, altered metabolism and deregulated mitophagy
Kyohei Fujita, Patrick Desmond, Jordan Blondelle, Matúš Soták, Meenu Rohini Rajan, Madison Clark, Eric Esteve, Yunghang Chan, Yusu Gu, Valeria Marrocco, Nancy D. Dalton, Majid Ghassemian, Aryanne Do, Matthew Klos, Kirk L. Peterson, Farah Sheikh, Yoshitake Cho, View ORCID ProfileEmma Börgeson, View ORCID ProfileStephan Lange
doi: https://doi.org/10.1101/2022.08.24.505098
Kyohei Fujita
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Patrick Desmond
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Jordan Blondelle
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Matúš Soták
2Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
3Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden
4Region Vaestra Goetaland, Sahlgrenska University Hospital, Department of Clinical Physiology, Gothenburg, Sweden
Meenu Rohini Rajan
2Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
3Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden
4Region Vaestra Goetaland, Sahlgrenska University Hospital, Department of Clinical Physiology, Gothenburg, Sweden
Madison Clark
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
2Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
Eric Esteve
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
5PhyMedExp, University of Montpellier, CNRS, INSERM, CHRU Montpellier, Montpellier, France
Yunghang Chan
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Yusu Gu
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Valeria Marrocco
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Nancy D. Dalton
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Majid Ghassemian
6Department of Chemistry and Biochemistry, UC San Diego, La Jolla, USA
Aryanne Do
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Matthew Klos
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Kirk L. Peterson
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Farah Sheikh
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Yoshitake Cho
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
Emma Börgeson
2Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
3Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden
4Region Vaestra Goetaland, Sahlgrenska University Hospital, Department of Clinical Physiology, Gothenburg, Sweden
Stephan Lange
1Division of Cardiology, School of Medicine, UC San Diego, La Jolla, USA
2Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
Article usage
Posted August 26, 2022.
Combined loss of obscurin and obscurin-like 1 in murine hearts results in diastolic dysfunction, altered metabolism and deregulated mitophagy
Kyohei Fujita, Patrick Desmond, Jordan Blondelle, Matúš Soták, Meenu Rohini Rajan, Madison Clark, Eric Esteve, Yunghang Chan, Yusu Gu, Valeria Marrocco, Nancy D. Dalton, Majid Ghassemian, Aryanne Do, Matthew Klos, Kirk L. Peterson, Farah Sheikh, Yoshitake Cho, Emma Börgeson, Stephan Lange
bioRxiv 2022.08.24.505098; doi: https://doi.org/10.1101/2022.08.24.505098
Combined loss of obscurin and obscurin-like 1 in murine hearts results in diastolic dysfunction, altered metabolism and deregulated mitophagy
Kyohei Fujita, Patrick Desmond, Jordan Blondelle, Matúš Soták, Meenu Rohini Rajan, Madison Clark, Eric Esteve, Yunghang Chan, Yusu Gu, Valeria Marrocco, Nancy D. Dalton, Majid Ghassemian, Aryanne Do, Matthew Klos, Kirk L. Peterson, Farah Sheikh, Yoshitake Cho, Emma Börgeson, Stephan Lange
bioRxiv 2022.08.24.505098; doi: https://doi.org/10.1101/2022.08.24.505098
Subject Area
Subject Areas
- Biochemistry (11752)
- Bioengineering (8752)
- Bioinformatics (29200)
- Biophysics (14974)
- Cancer Biology (12096)
- Cell Biology (17411)
- Clinical Trials (138)
- Developmental Biology (9421)
- Ecology (14182)
- Epidemiology (2067)
- Evolutionary Biology (18308)
- Genetics (12245)
- Genomics (16803)
- Immunology (11869)
- Microbiology (28097)
- Molecular Biology (11594)
- Neuroscience (60969)
- Paleontology (451)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2886)
- Systems Biology (7340)
- Zoology (1651)