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Enhancer Reprogramming in Melanoma Immune Checkpoint Therapy Resistance
Mayinuer Maitituoheti, Alvin Shi, Ming Tang, Li-Lun Ho, Christopher Terranova, Kyriaki Galani, Emily Z. Keung, Caitlin A. Creasy, Manrong Wu, Jiajia Chen, Nana Chen, Anand K. Singh, Apoorvi Chaudhri, Nazanin E. Anvar, Giuseppe Tarantino, Jiekun Yang, Sharmistha Sarkar, Shan Jiang, Jared Malke, Lauren Haydu, Elizabeth Burton, Michael A. Davies, Jeffrey E. Gershenwald, Patrick Hwu, Alexander Lazar, Jaime H. Cheah, Christian K. Soule, Stuart S. Levine, Chantale Bernatchez, Srinivas V. Saladi, David Liu, Jennifer Wargo, Genevieve M. Boland, Manolis Kellis, Kunal Rai
doi: https://doi.org/10.1101/2022.08.31.506051
Mayinuer Maitituoheti
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
2Immunobiology and Transplant Science Center and Department of Surgery, Houston Methodist Hospital, Houston, TX
Alvin Shi
3Department of Computer Science, Massachusetts Institute of Technology, Boston, MA
12GRAIL, LLC. Menlo Park, CA
Ming Tang
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
13Immunitas, Boston, MA
Li-Lun Ho
3Department of Computer Science, Massachusetts Institute of Technology, Boston, MA
Christopher Terranova
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Kyriaki Galani
3Department of Computer Science, Massachusetts Institute of Technology, Boston, MA
Emily Z. Keung
4Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Caitlin A. Creasy
5Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Manrong Wu
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Jiajia Chen
6Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
Nana Chen
7Department of Otolaryngology Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Broad Institute of Harvard and MIT
Anand K. Singh
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Apoorvi Chaudhri
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
5Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Nazanin E. Anvar
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Giuseppe Tarantino
6Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
Jiekun Yang
3Department of Computer Science, Massachusetts Institute of Technology, Boston, MA
Sharmistha Sarkar
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Shan Jiang
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Jared Malke
4Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Lauren Haydu
5Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Elizabeth Burton
5Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Michael A. Davies
5Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Jeffrey E. Gershenwald
5Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Patrick Hwu
5Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
8Department of Cutaneous Oncology, Moffitt Cancer Center, Tampa, FL
Alexander Lazar
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
9Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX
Jaime H. Cheah
10Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA
Christian K. Soule
10Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA
Stuart S. Levine
10Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA
Chantale Bernatchez
5Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Srinivas V. Saladi
7Department of Otolaryngology Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Broad Institute of Harvard and MIT
David Liu
6Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
Jennifer Wargo
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
4Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Genevieve M. Boland
11Department of Surgery, Massachusetts General Hospital, Boston, MA
Manolis Kellis
3Department of Computer Science, Massachusetts Institute of Technology, Boston, MA
Kunal Rai
1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Article usage
Posted September 03, 2022.
Enhancer Reprogramming in Melanoma Immune Checkpoint Therapy Resistance
Mayinuer Maitituoheti, Alvin Shi, Ming Tang, Li-Lun Ho, Christopher Terranova, Kyriaki Galani, Emily Z. Keung, Caitlin A. Creasy, Manrong Wu, Jiajia Chen, Nana Chen, Anand K. Singh, Apoorvi Chaudhri, Nazanin E. Anvar, Giuseppe Tarantino, Jiekun Yang, Sharmistha Sarkar, Shan Jiang, Jared Malke, Lauren Haydu, Elizabeth Burton, Michael A. Davies, Jeffrey E. Gershenwald, Patrick Hwu, Alexander Lazar, Jaime H. Cheah, Christian K. Soule, Stuart S. Levine, Chantale Bernatchez, Srinivas V. Saladi, David Liu, Jennifer Wargo, Genevieve M. Boland, Manolis Kellis, Kunal Rai
bioRxiv 2022.08.31.506051; doi: https://doi.org/10.1101/2022.08.31.506051
Enhancer Reprogramming in Melanoma Immune Checkpoint Therapy Resistance
Mayinuer Maitituoheti, Alvin Shi, Ming Tang, Li-Lun Ho, Christopher Terranova, Kyriaki Galani, Emily Z. Keung, Caitlin A. Creasy, Manrong Wu, Jiajia Chen, Nana Chen, Anand K. Singh, Apoorvi Chaudhri, Nazanin E. Anvar, Giuseppe Tarantino, Jiekun Yang, Sharmistha Sarkar, Shan Jiang, Jared Malke, Lauren Haydu, Elizabeth Burton, Michael A. Davies, Jeffrey E. Gershenwald, Patrick Hwu, Alexander Lazar, Jaime H. Cheah, Christian K. Soule, Stuart S. Levine, Chantale Bernatchez, Srinivas V. Saladi, David Liu, Jennifer Wargo, Genevieve M. Boland, Manolis Kellis, Kunal Rai
bioRxiv 2022.08.31.506051; doi: https://doi.org/10.1101/2022.08.31.506051
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