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Plant production of high affinity nanobodies that block SARS-CoV-2 spike protein binding with its receptor, human angiotensin converting enzyme

View ORCID ProfileMarco Pitino, View ORCID ProfileLaura A. Fleites, Lauren Shrum, View ORCID ProfileMichelle Heck, View ORCID ProfileRobert G. Shatters Jr.
doi: https://doi.org/10.1101/2022.09.03.506425
Marco Pitino
1AgroSource, Inc., Jupiter, FL, USA
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Laura A. Fleites
1AgroSource, Inc., Jupiter, FL, USA
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Lauren Shrum
1AgroSource, Inc., Jupiter, FL, USA
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Michelle Heck
2Emerging Pests and Pathogens Research Unit, USDA Agricultural Research Service, Ithaca, NY, USA
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Robert G. Shatters Jr.
3U.S. Horticultural Research Laboratory, Unit of Subtropical Insects and Horticulture, USDA Agricultural Research Service, Fort Pierce, FL, USA
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  • ORCID record for Robert G. Shatters Jr.
  • For correspondence: Robert.Shatters@USDA.gov
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Article Information

doi 
https://doi.org/10.1101/2022.09.03.506425
History 
  • September 3, 2022.

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  • You are currently viewing Version 1 of this article (September 3, 2022 - 14:21).
  • View Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. This article is a US Government work. It is not subject to copyright under 17 USC 105 and is also made available for use under a CC0 license.

Author Information

  1. Marco Pitino1,
  2. Laura A. Fleites1,
  3. Lauren Shrum1,
  4. Michelle Heck2 and
  5. Robert G. Shatters Jr.3,*
  1. 1AgroSource, Inc., Jupiter, FL, USA
  2. 2Emerging Pests and Pathogens Research Unit, USDA Agricultural Research Service, Ithaca, NY, USA
  3. 3U.S. Horticultural Research Laboratory, Unit of Subtropical Insects and Horticulture, USDA Agricultural Research Service, Fort Pierce, FL, USA
  1. ↵*Correspondence:
    Robert G. Shatters, Jr. Robert.Shatters{at}USDA.gov
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Posted September 03, 2022.
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Plant production of high affinity nanobodies that block SARS-CoV-2 spike protein binding with its receptor, human angiotensin converting enzyme
Marco Pitino, Laura A. Fleites, Lauren Shrum, Michelle Heck, Robert G. Shatters Jr.
bioRxiv 2022.09.03.506425; doi: https://doi.org/10.1101/2022.09.03.506425
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Plant production of high affinity nanobodies that block SARS-CoV-2 spike protein binding with its receptor, human angiotensin converting enzyme
Marco Pitino, Laura A. Fleites, Lauren Shrum, Michelle Heck, Robert G. Shatters Jr.
bioRxiv 2022.09.03.506425; doi: https://doi.org/10.1101/2022.09.03.506425

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