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The UIP honeycomb airway cells are the site of mucin biogenesis with deranged cilia

View ORCID ProfileJeremy A. Herrera, Lewis A. Dingle, M. Angeles Montero, Rajamiyer V. Venkateswaran, View ORCID ProfileJohn F. Blaikley, Felice Granato, Stella Pearson, Craig Lawless, View ORCID ProfileDavid J. Thornton
doi: https://doi.org/10.1101/2022.09.03.506451
Jeremy A. Herrera
1The Wellcome Centre for Cell-Matrix Research, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
4Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
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  • ORCID record for Jeremy A. Herrera
  • For correspondence: Jeremy.Herrera@manchester.ac.uk
Lewis A. Dingle
3Blond McIndoe Laboratories, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
4Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
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M. Angeles Montero
5Manchester University NHS Foundation Trust, Manchester, Greater Manchester, United Kingdom
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Rajamiyer V. Venkateswaran
4Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
5Manchester University NHS Foundation Trust, Manchester, Greater Manchester, United Kingdom
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John F. Blaikley
4Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
5Manchester University NHS Foundation Trust, Manchester, Greater Manchester, United Kingdom
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Felice Granato
5Manchester University NHS Foundation Trust, Manchester, Greater Manchester, United Kingdom
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Stella Pearson
1The Wellcome Centre for Cell-Matrix Research, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
2Lydia Becker Institute of Immunology and Inflammation, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
4Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
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Craig Lawless
1The Wellcome Centre for Cell-Matrix Research, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
4Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
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David J. Thornton
1The Wellcome Centre for Cell-Matrix Research, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
2Lydia Becker Institute of Immunology and Inflammation, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
4Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
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Article Information

doi 
https://doi.org/10.1101/2022.09.03.506451
History 
  • September 5, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Jeremy A. Herrera1,4,†,
  2. Lewis A. Dingle3,4,
  3. M. Angeles Montero5,
  4. Rajamiyer V. Venkateswaran4,5,
  5. John F. Blaikley4,5,
  6. Felice Granato5,
  7. Stella Pearson1,2,4,
  8. Craig Lawless1,4 and
  9. David J. Thornton1,2,4
  1. 1The Wellcome Centre for Cell-Matrix Research, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
  2. 2Lydia Becker Institute of Immunology and Inflammation, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
  3. 3Blond McIndoe Laboratories, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
  4. 4Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, Great Manchester, United Kingdom
  5. 5Manchester University NHS Foundation Trust, Manchester, Greater Manchester, United Kingdom
  1. ↵†Corresponding author: Jeremy.Herrera{at}manchester.ac.uk, (+44) 0161 275 5072, University of Manchester, 4.019 AV Hill, Oxford Road, Manchester, Greater Manchester, M13 9PT, United Kingdom
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Posted September 05, 2022.
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The UIP honeycomb airway cells are the site of mucin biogenesis with deranged cilia
Jeremy A. Herrera, Lewis A. Dingle, M. Angeles Montero, Rajamiyer V. Venkateswaran, John F. Blaikley, Felice Granato, Stella Pearson, Craig Lawless, David J. Thornton
bioRxiv 2022.09.03.506451; doi: https://doi.org/10.1101/2022.09.03.506451
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The UIP honeycomb airway cells are the site of mucin biogenesis with deranged cilia
Jeremy A. Herrera, Lewis A. Dingle, M. Angeles Montero, Rajamiyer V. Venkateswaran, John F. Blaikley, Felice Granato, Stella Pearson, Craig Lawless, David J. Thornton
bioRxiv 2022.09.03.506451; doi: https://doi.org/10.1101/2022.09.03.506451

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