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Pseudokinase HPO-11 inhibits nonsense-mediated decay to ensure genome stability in C. elegans

Qian Zhao, Erika D Gromoff, Wei Yang, Jennifer Schwarz, Lena Tittel, Ekkehard Schulze, View ORCID ProfileBettina Warscheid, View ORCID ProfileRalf Baumeister, View ORCID ProfileWenjing Qi
doi: https://doi.org/10.1101/2022.09.04.506508
Qian Zhao
1Bioinformatics and Molecular Genetics, Institute of Biology III, Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany
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Erika D Gromoff
1Bioinformatics and Molecular Genetics, Institute of Biology III, Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany
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Wei Yang
1Bioinformatics and Molecular Genetics, Institute of Biology III, Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany
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Jennifer Schwarz
2Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany
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Lena Tittel
1Bioinformatics and Molecular Genetics, Institute of Biology III, Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany
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Ekkehard Schulze
1Bioinformatics and Molecular Genetics, Institute of Biology III, Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany
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Bettina Warscheid
2Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany
3Signalling Research Centers BIOSS and CIBSS, Albert-Ludwigs-University Freiburg, Germany
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Ralf Baumeister
1Bioinformatics and Molecular Genetics, Institute of Biology III, Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany
3Signalling Research Centers BIOSS and CIBSS, Albert-Ludwigs-University Freiburg, Germany
4Center for Biochemistry and Molecular Cell Research, Faculty of Medicine, Albert-Ludwigs-University Freiburg, Germany
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  • ORCID record for Ralf Baumeister
  • For correspondence: wenjing.qi@biologie.uni-freiburg.de baumeister@celegans.de
Wenjing Qi
1Bioinformatics and Molecular Genetics, Institute of Biology III, Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany
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  • ORCID record for Wenjing Qi
  • For correspondence: wenjing.qi@biologie.uni-freiburg.de baumeister@celegans.de
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Article Information

doi 
https://doi.org/10.1101/2022.09.04.506508
History 
  • September 4, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Qian Zhao1,
  2. Erika D Gromoff1,
  3. Wei Yang1,
  4. Jennifer Schwarz2,
  5. Lena Tittel1,
  6. Ekkehard Schulze1,
  7. Bettina Warscheid2,3,
  8. Ralf Baumeister1,3,4,# and
  9. Wenjing Qi1,#
  1. 1Bioinformatics and Molecular Genetics, Institute of Biology III, Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany
  2. 2Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany
  3. 3Signalling Research Centers BIOSS and CIBSS, Albert-Ludwigs-University Freiburg, Germany
  4. 4Center for Biochemistry and Molecular Cell Research, Faculty of Medicine, Albert-Ludwigs-University Freiburg, Germany
  1. ↵# Correspondence: wenjing.qi{at}biologie.uni-freiburg.de, baumeister{at}celegans.de, Bio3/Bio-informatics and Molecular Genetics, University of Freiburg, Schänzlestrasse 1, D-79104 Freiburg, Germany
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Posted September 04, 2022.
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Pseudokinase HPO-11 inhibits nonsense-mediated decay to ensure genome stability in C. elegans
Qian Zhao, Erika D Gromoff, Wei Yang, Jennifer Schwarz, Lena Tittel, Ekkehard Schulze, Bettina Warscheid, Ralf Baumeister, Wenjing Qi
bioRxiv 2022.09.04.506508; doi: https://doi.org/10.1101/2022.09.04.506508
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Pseudokinase HPO-11 inhibits nonsense-mediated decay to ensure genome stability in C. elegans
Qian Zhao, Erika D Gromoff, Wei Yang, Jennifer Schwarz, Lena Tittel, Ekkehard Schulze, Bettina Warscheid, Ralf Baumeister, Wenjing Qi
bioRxiv 2022.09.04.506508; doi: https://doi.org/10.1101/2022.09.04.506508

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