Conformational Changes Regulate Metal Coordination in the Catalytic Sites of Cas9

Anuska Das; Jay Rai; Mitchell O. Roth; Yuerong Shu; Megan L. Medina; MacKenzie R. Barakat; Hong Li

doi:10.1101/2022.09.10.507422

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Conformational Changes Regulate Metal Coordination in the Catalytic Sites of Cas9

Anuska Das, Jay Rai, Mitchell O. Roth, Yuerong Shu, Megan L. Medina, MacKenzie R. Barakat, View ORCID ProfileHong Li

doi: https://doi.org/10.1101/2022.09.10.507422

Anuska Das

1Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA

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Jay Rai

1Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA

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Mitchell O. Roth

1Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA

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Yuerong Shu

1Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA

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Megan L. Medina

2Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA

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MacKenzie R. Barakat

1Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA

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Hong Li

1Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA

2Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA

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ORCID record for Hong Li
For correspondence: hong.li@fsu.edu

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Posted September 11, 2022.

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Conformational Changes Regulate Metal Coordination in the Catalytic Sites of Cas9

Anuska Das, Jay Rai, Mitchell O. Roth, Yuerong Shu, Megan L. Medina, MacKenzie R. Barakat, Hong Li

bioRxiv 2022.09.10.507422; doi: https://doi.org/10.1101/2022.09.10.507422

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Conformational Changes Regulate Metal Coordination in the Catalytic Sites of Cas9

Anuska Das, Jay Rai, Mitchell O. Roth, Yuerong Shu, Megan L. Medina, MacKenzie R. Barakat, Hong Li

bioRxiv 2022.09.10.507422; doi: https://doi.org/10.1101/2022.09.10.507422

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