New Results
Recycling upstream redox enzymes expands the regioselectivity of cycloaddition in pseudo-aspidosperma alkaloid biosynthesis
Mohamed O. Kamileen, Matthew D. DeMars II, Benke Hong, Yoko Nakamura, Christian Paetz, Benjamin R. Lichman, Prashant D. Sonawane, Lorenzo Caputi, View ORCID ProfileSarah E. O’Connor
doi: https://doi.org/10.1101/2022.09.13.507834
Mohamed O. Kamileen
1Department of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, Jena 07745 Germany
3Centre for Novel Agricultural Products, Department of Biology, University of York, York, UK
Matthew D. DeMars II
1Department of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, Jena 07745 Germany
Benke Hong
1Department of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, Jena 07745 Germany
Yoko Nakamura
1Department of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, Jena 07745 Germany
2Research Group Biosynthesis and NMR, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, Jena 07745 Germany
Christian Paetz
2Research Group Biosynthesis and NMR, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, Jena 07745 Germany
Benjamin R. Lichman
3Centre for Novel Agricultural Products, Department of Biology, University of York, York, UK
Prashant D. Sonawane
1Department of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, Jena 07745 Germany
Lorenzo Caputi
1Department of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, Jena 07745 Germany
Sarah E. O’Connor
1Department of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, Jena 07745 Germany
Posted September 13, 2022.
Recycling upstream redox enzymes expands the regioselectivity of cycloaddition in pseudo-aspidosperma alkaloid biosynthesis
Mohamed O. Kamileen, Matthew D. DeMars II, Benke Hong, Yoko Nakamura, Christian Paetz, Benjamin R. Lichman, Prashant D. Sonawane, Lorenzo Caputi, Sarah E. O’Connor
bioRxiv 2022.09.13.507834; doi: https://doi.org/10.1101/2022.09.13.507834
Recycling upstream redox enzymes expands the regioselectivity of cycloaddition in pseudo-aspidosperma alkaloid biosynthesis
Mohamed O. Kamileen, Matthew D. DeMars II, Benke Hong, Yoko Nakamura, Christian Paetz, Benjamin R. Lichman, Prashant D. Sonawane, Lorenzo Caputi, Sarah E. O’Connor
bioRxiv 2022.09.13.507834; doi: https://doi.org/10.1101/2022.09.13.507834
Subject Area
Subject Areas
- Biochemistry (11752)
- Bioengineering (8752)
- Bioinformatics (29200)
- Biophysics (14974)
- Cancer Biology (12096)
- Cell Biology (17411)
- Clinical Trials (138)
- Developmental Biology (9421)
- Ecology (14182)
- Epidemiology (2067)
- Evolutionary Biology (18308)
- Genetics (12245)
- Genomics (16803)
- Immunology (11869)
- Microbiology (28097)
- Molecular Biology (11594)
- Neuroscience (60969)
- Paleontology (451)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2886)
- Systems Biology (7340)
- Zoology (1651)