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A p21-GFP zebrafish model of senescence for rapid testing of senolytics in vivo
Samir Morsli, Catarina M. Henriques, Pamela S Ellis, Heather Mortiboys, Sarah Baxendale, Catherine Loynes, View ORCID ProfileStephen A. Renshaw, View ORCID ProfileIlaria Bellantuono
doi: https://doi.org/10.1101/2022.09.19.506911
Samir Morsli
1The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH
2Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH
4Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ
Catarina M. Henriques
1The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH
2Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH
3Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield S10 2RX
Pamela S Ellis
1The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH
3Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield S10 2RX
Heather Mortiboys
2Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH
4Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ
Sarah Baxendale
1The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH
2Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH
Catherine Loynes
1The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH
5Department of Infection, Immunity and Cardiovascular Disease, Beech Hill Road, Sheffield, S10 2RX
Stephen A. Renshaw
1The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH
2Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH
5Department of Infection, Immunity and Cardiovascular Disease, Beech Hill Road, Sheffield, S10 2RX
Ilaria Bellantuono
2Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH
3Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield S10 2RX
Posted September 19, 2022.
A p21-GFP zebrafish model of senescence for rapid testing of senolytics in vivo
Samir Morsli, Catarina M. Henriques, Pamela S Ellis, Heather Mortiboys, Sarah Baxendale, Catherine Loynes, Stephen A. Renshaw, Ilaria Bellantuono
bioRxiv 2022.09.19.506911; doi: https://doi.org/10.1101/2022.09.19.506911
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