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Murine breast cancers disorganize the liver transcriptome in zonated manners

Alexis Vandenbon, Rin Mizuno, Riyo Konishi, Masaya Onishi, Kyoko Masuda, Yuka Kobayashi, Hiroshi Kawamoto, Ayako Suzuki, Masahito Shimizu, Yasuhito Tanaka, Yutaka Suzuki, Shinpei Kawaoka
doi: https://doi.org/10.1101/2022.09.27.509354
Alexis Vandenbon
1Laboratory of Tissue Homeostasis, Institute for Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan
2Institute for Liberal Arts and Sciences, Kyoto University, Kyoto, 606-8507, Japan
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  • For correspondence: kawaokashinpei@gmail.com alexis.vandenbon@gmail.com ysuzuki@edu.k.u-tokyo.ac.jp
Rin Mizuno
3Inter-Organ Communication Research Team, Institute for Life and Medical Sciences, Kyoto, 606-8507, Japan
4Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan
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Riyo Konishi
3Inter-Organ Communication Research Team, Institute for Life and Medical Sciences, Kyoto, 606-8507, Japan
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Masaya Onishi
5Graduate School of Frontier Science, The University of Tokyo, Chiba, 277-8562, Japan
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Kyoko Masuda
7Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan
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Yuka Kobayashi
7Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan
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Hiroshi Kawamoto
7Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan
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Ayako Suzuki
5Graduate School of Frontier Science, The University of Tokyo, Chiba, 277-8562, Japan
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Masahito Shimizu
8Department of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, 501-1194, Japan
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Yasuhito Tanaka
9Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University, 860-8556, Japan
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Yutaka Suzuki
5Graduate School of Frontier Science, The University of Tokyo, Chiba, 277-8562, Japan
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  • For correspondence: kawaokashinpei@gmail.com alexis.vandenbon@gmail.com ysuzuki@edu.k.u-tokyo.ac.jp
Shinpei Kawaoka
3Inter-Organ Communication Research Team, Institute for Life and Medical Sciences, Kyoto, 606-8507, Japan
6Department of Integrative Bioanalytics, Institute of Development, Aging and Cancer (IDAC), Tohoku University, Sendai 980-8575, Japan
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  • For correspondence: kawaokashinpei@gmail.com alexis.vandenbon@gmail.com ysuzuki@edu.k.u-tokyo.ac.jp
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Article Information

doi 
https://doi.org/10.1101/2022.09.27.509354
History 
  • September 28, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Alexis Vandenbon1,2,#,*,
  2. Rin Mizuno3,4,#,
  3. Riyo Konishi3,#,
  4. Masaya Onishi5,#,
  5. Kyoko Masuda7,
  6. Yuka Kobayashi7,
  7. Hiroshi Kawamoto7,
  8. Ayako Suzuki5,
  9. Masahito Shimizu8,
  10. Yasuhito Tanaka9,
  11. Yutaka Suzuki5,* and
  12. Shinpei Kawaoka3,6,*
  1. 1Laboratory of Tissue Homeostasis, Institute for Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan
  2. 2Institute for Liberal Arts and Sciences, Kyoto University, Kyoto, 606-8507, Japan
  3. 3Inter-Organ Communication Research Team, Institute for Life and Medical Sciences, Kyoto, 606-8507, Japan
  4. 4Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan
  5. 5Graduate School of Frontier Science, The University of Tokyo, Chiba, 277-8562, Japan
  6. 6Department of Integrative Bioanalytics, Institute of Development, Aging and Cancer (IDAC), Tohoku University, Sendai 980-8575, Japan
  7. 7Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan
  8. 8Department of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, 501-1194, Japan
  9. 9Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University, 860-8556, Japan
  1. ↵*Corresponding Authors: Shinpei Kawaoka, Ph.D. Department of Integrative Bioanalytics, Institute of Development, Aging and Cancer (IDAC), Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan, TEL: +81-22-717-8568, FAX: +81-22-717-8488, Email: kawaokashinpei{at}gmail.com, Inter-Organ Communication Research Team, Institute for Life and Medical Sciences, Kyoto University, 53 Shogoin-kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan, TEL: +81-75-751-4804, FAX: +81-75-751-3839, Email: kawaokashinpei{at}gmail.com, Alexis Vandenbon, Ph.D. Laboratory of Tissue Homeostasis, Institute for Life and Medical Sciences, Kyoto University, 53 Shogoin-kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan TEL: +81-75-751-3991, Email: alexis.vandenbon{at}gmail.com, Yutaka Suzuki, Ph.D. Laboratory of Systems Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 6-2-3 Kashiwa-no-ha, Kashiwa city, Chiba, 277-8562, Japan, TEL: +81-4-7136-3607, Email: ysuzuki{at}edu.k.u-tokyo.ac.jp
  1. ↵# These authors equally contributed to this work.

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Murine breast cancers disorganize the liver transcriptome in zonated manners
Alexis Vandenbon, Rin Mizuno, Riyo Konishi, Masaya Onishi, Kyoko Masuda, Yuka Kobayashi, Hiroshi Kawamoto, Ayako Suzuki, Masahito Shimizu, Yasuhito Tanaka, Yutaka Suzuki, Shinpei Kawaoka
bioRxiv 2022.09.27.509354; doi: https://doi.org/10.1101/2022.09.27.509354
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Murine breast cancers disorganize the liver transcriptome in zonated manners
Alexis Vandenbon, Rin Mizuno, Riyo Konishi, Masaya Onishi, Kyoko Masuda, Yuka Kobayashi, Hiroshi Kawamoto, Ayako Suzuki, Masahito Shimizu, Yasuhito Tanaka, Yutaka Suzuki, Shinpei Kawaoka
bioRxiv 2022.09.27.509354; doi: https://doi.org/10.1101/2022.09.27.509354

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