Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease

Benjamin Ober-Reynolds; Chen Wang; Justin M. Ko; Eon J. Rios; Sumaira Z. Aasi; Mark M. Davis; Anthony E. Oro; William J. Greenleaf

doi:10.1101/2022.09.28.509620

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Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease

Benjamin Ober-Reynolds, Chen Wang, Justin M. Ko, Eon J. Rios, Sumaira Z. Aasi, Mark M. Davis, Anthony E. Oro, William J. Greenleaf

doi: https://doi.org/10.1101/2022.09.28.509620

Benjamin Ober-Reynolds

1Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA

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Chen Wang

2Department of Dermatology, School of Medicine, Stanford University, Stanford, CA, USA.

3Institute of Immunity, Transplantation and Infection, School of Medicine, Stanford University, Stanford CA, USA.

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Justin M. Ko

2Department of Dermatology, School of Medicine, Stanford University, Stanford, CA, USA.

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Eon J. Rios

2Department of Dermatology, School of Medicine, Stanford University, Stanford, CA, USA.

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Sumaira Z. Aasi

2Department of Dermatology, School of Medicine, Stanford University, Stanford, CA, USA.

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Mark M. Davis

3Institute of Immunity, Transplantation and Infection, School of Medicine, Stanford University, Stanford CA, USA.

4Department of Microbiology and Immunology, School of Medicine, Stanford University, Stanford, CA, USA

5Howard Hughes Medical Institute, School of Medicine, Stanford University, Stanford, CA, USA

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Anthony E. Oro

2Department of Dermatology, School of Medicine, Stanford University, Stanford, CA, USA.

6Program in Epithelial Biology, Stanford University School of Medicine, 269 Campus Drive, Stanford, CA 94305, USA

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William J. Greenleaf

1Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA

7Department of Applied Physics, Stanford University, Stanford, CA 94305, USA

8Chan Zuckerberg Biohub, San Francisco, CA 94158, USA

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For correspondence: wjg@stanford.edu

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Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease

Benjamin Ober-Reynolds, Chen Wang, Justin M. Ko, Eon J. Rios, Sumaira Z. Aasi, Mark M. Davis, Anthony E. Oro, William J. Greenleaf

bioRxiv 2022.09.28.509620; doi: https://doi.org/10.1101/2022.09.28.509620

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Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease

Benjamin Ober-Reynolds, Chen Wang, Justin M. Ko, Eon J. Rios, Sumaira Z. Aasi, Mark M. Davis, Anthony E. Oro, William J. Greenleaf

bioRxiv 2022.09.28.509620; doi: https://doi.org/10.1101/2022.09.28.509620

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