Positive allosteric modulation of α5-GABA A Receptor in the 5XFAD mouse model has cognitive and neurotrophic benefits

Ashley M. Bernardo; Michael Marcotte; Kayla Wong; Dishary Sharmin; Kamal Prandey; James M. Cook; Etienne Sibille; Thomas D. Prevot

doi:10.1101/2022.09.30.510361

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Positive allosteric modulation of α5-GABA A Receptor in the 5XFAD mouse model has cognitive and neurotrophic benefits

Ashley M. Bernardo, Michael Marcotte, Kayla Wong, Dishary Sharmin, Kamal Prandey, James M. Cook, Etienne Sibille, View ORCID ProfileThomas D. Prevot

doi: https://doi.org/10.1101/2022.09.30.510361

Ashley M. Bernardo

1Campbell Family Mental Health Research Institute of CAMH, Toronto, Canada

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Michael Marcotte

1Campbell Family Mental Health Research Institute of CAMH, Toronto, Canada

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Kayla Wong

1Campbell Family Mental Health Research Institute of CAMH, Toronto, Canada

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Dishary Sharmin

2Department of Chemistry and Biochemistry, University of Wisconsin–Milwaukee, Milwaukee, USA

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Kamal Prandey

2Department of Chemistry and Biochemistry, University of Wisconsin–Milwaukee, Milwaukee, USA

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James M. Cook

2Department of Chemistry and Biochemistry, University of Wisconsin–Milwaukee, Milwaukee, USA

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Etienne Sibille

1Campbell Family Mental Health Research Institute of CAMH, Toronto, Canada

3Department of Psychiatry, University of Toronto, Toronto, Canada

4Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada

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Thomas D. Prevot

1Campbell Family Mental Health Research Institute of CAMH, Toronto, Canada

3Department of Psychiatry, University of Toronto, Toronto, Canada

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ORCID record for Thomas D. Prevot
For correspondence: thomas.prevot@camh.ca

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Positive allosteric modulation of α5-GABA A Receptor in the 5XFAD mouse model has cognitive and neurotrophic benefits

Ashley M. Bernardo, Michael Marcotte, Kayla Wong, Dishary Sharmin, Kamal Prandey, James M. Cook, Etienne Sibille, Thomas D. Prevot

bioRxiv 2022.09.30.510361; doi: https://doi.org/10.1101/2022.09.30.510361

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Positive allosteric modulation of α5-GABA A Receptor in the 5XFAD mouse model has cognitive and neurotrophic benefits

Ashley M. Bernardo, Michael Marcotte, Kayla Wong, Dishary Sharmin, Kamal Prandey, James M. Cook, Etienne Sibille, Thomas D. Prevot

bioRxiv 2022.09.30.510361; doi: https://doi.org/10.1101/2022.09.30.510361

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