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Zebrafish screen of high-confidence effector genes at insomnia GWAS loci implicates conserved regulators of sleep-wake behaviors
View ORCID ProfileAmber J. Zimmerman, Fusun Doldur-Balli, Brendan T. Keenan, Zoe Y. Shetty, Justin Palermo, Alessandra Chesi, Shilpa Sonti, Matthew C. Pahl, Elizabeth B. Brown, James A. Pippin, Andrew D. Wells, Olivia J. Veatch, Diego R. Mazzotti, Anitra Krishnan, Phillip R. Gehrman, Alex C. Keene, Struan F.A. Grant, Allan I. Pack
doi: https://doi.org/10.1101/2022.10.05.511011
Amber J. Zimmerman
aCenter for Spatial and Functional Genomics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
bDivision of Sleep Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, PA, United States
Fusun Doldur-Balli
bDivision of Sleep Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, PA, United States
Brendan T. Keenan
bDivision of Sleep Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, PA, United States
Zoe Y. Shetty
bDivision of Sleep Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, PA, United States
Justin Palermo
cDepartment of Biology, Texas A&M University, College Station, TX, United States
Alessandra Chesi
aCenter for Spatial and Functional Genomics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
dDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
Shilpa Sonti
aCenter for Spatial and Functional Genomics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Matthew C. Pahl
aCenter for Spatial and Functional Genomics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Elizabeth B. Brown
cDepartment of Biology, Texas A&M University, College Station, TX, United States
James A. Pippin
aCenter for Spatial and Functional Genomics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Andrew D. Wells
aCenter for Spatial and Functional Genomics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
dDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
eDepartment of Pathology, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Olivia J. Veatch
fDepartment of Psychiatry and Behavioral Sciences, University of Kansas Medical Center, Kansas City, KS, USA
Diego R. Mazzotti
gDivision of Medical Informatics, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA
hDivision of Pulmonary Critical Care and Sleep Medicine, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA
Anitra Krishnan
bDivision of Sleep Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, PA, United States
Phillip R. Gehrman
iDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, PA, USA
Alex C. Keene
cDepartment of Biology, Texas A&M University, College Station, TX, United States
Struan F.A. Grant
aCenter for Spatial and Functional Genomics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
jDepartment of Pediatrics, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
kDivision of Human Genetics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
lDepartment of Genetics, University of Pennsylvania, Philadelphia, PA, USA
Allan I. Pack
bDivision of Sleep Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, PA, United States
Posted November 28, 2022.
Zebrafish screen of high-confidence effector genes at insomnia GWAS loci implicates conserved regulators of sleep-wake behaviors
Amber J. Zimmerman, Fusun Doldur-Balli, Brendan T. Keenan, Zoe Y. Shetty, Justin Palermo, Alessandra Chesi, Shilpa Sonti, Matthew C. Pahl, Elizabeth B. Brown, James A. Pippin, Andrew D. Wells, Olivia J. Veatch, Diego R. Mazzotti, Anitra Krishnan, Phillip R. Gehrman, Alex C. Keene, Struan F.A. Grant, Allan I. Pack
bioRxiv 2022.10.05.511011; doi: https://doi.org/10.1101/2022.10.05.511011
Zebrafish screen of high-confidence effector genes at insomnia GWAS loci implicates conserved regulators of sleep-wake behaviors
Amber J. Zimmerman, Fusun Doldur-Balli, Brendan T. Keenan, Zoe Y. Shetty, Justin Palermo, Alessandra Chesi, Shilpa Sonti, Matthew C. Pahl, Elizabeth B. Brown, James A. Pippin, Andrew D. Wells, Olivia J. Veatch, Diego R. Mazzotti, Anitra Krishnan, Phillip R. Gehrman, Alex C. Keene, Struan F.A. Grant, Allan I. Pack
bioRxiv 2022.10.05.511011; doi: https://doi.org/10.1101/2022.10.05.511011
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