Differential chondrogenic differentiation between iPSC-derived from healthy and OA cartilage is associated with changes in epigenetic regulation and metabolic transcriptomic signatures

Nazir M. Khan; Martha Elena Diaz-Hernandez; Samir Chihab; Priyanka Priyadarshani; Pallavi Bhattaram; Luke J. Mortensen; Rosa M Guzzo; Hicham Drissi

doi:10.1101/2022.10.14.512213

New Results

Differential chondrogenic differentiation between iPSC-derived from healthy and OA cartilage is associated with changes in epigenetic regulation and metabolic transcriptomic signatures

View ORCID ProfileNazir M. Khan, Martha Elena Diaz-Hernandez, Samir Chihab, Priyanka Priyadarshani, Pallavi Bhattaram, View ORCID ProfileLuke J. Mortensen, Rosa M Guzzo, Hicham Drissi

doi: https://doi.org/10.1101/2022.10.14.512213

Nazir M. Khan

1Department of Orthopaedics, Emory University, Atlanta, GA, USA

2Atlanta VA Medical Center, Decatur, GA, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Nazir M. Khan

Martha Elena Diaz-Hernandez

1Department of Orthopaedics, Emory University, Atlanta, GA, USA

2Atlanta VA Medical Center, Decatur, GA, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Samir Chihab

1Department of Orthopaedics, Emory University, Atlanta, GA, USA

2Atlanta VA Medical Center, Decatur, GA, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Priyanka Priyadarshani

3School of Chemical Materials and Biomedical Engineering, University of Georgia, Athens, GA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Pallavi Bhattaram

1Department of Orthopaedics, Emory University, Atlanta, GA, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Luke J. Mortensen

3School of Chemical Materials and Biomedical Engineering, University of Georgia, Athens, GA

4Regenerative Bioscience Center, E.L. Rhodes Center for ADS, University of Georgia, Athens, GA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Luke J. Mortensen

Rosa M Guzzo

5Department of Neuroscience, School of Medicine, University of Connecticut Health, Farmington, CT, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Hicham Drissi

1Department of Orthopaedics, Emory University, Atlanta, GA, USA

2Atlanta VA Medical Center, Decatur, GA, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: hicham.drissi@emory.edu

Abstract
Full Text
Info/History
Metrics
Preview PDF

Article usage

Article usage: October 2022 to September 2023

	Abstract	Full	Pdf
Oct 2022	402	7	234
Nov 2022	50	2	25
Dec 2022	26	11	16
Jan 2023	85	7	38
Feb 2023	23	5	48
Mar 2023	8	0	19
Apr 2023	16	2	15
May 2023	11	2	5
Jun 2023	11	1	5
Jul 2023	10	2	9
Aug 2023	9	3	11
Sep 2023	13	1	11

View the discussion thread.

PreviousNext

Posted October 14, 2022.

Download PDF

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Differential chondrogenic differentiation between iPSC-derived from healthy and OA cartilage is associated with changes in epigenetic regulation and metabolic transcriptomic signatures

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Differential chondrogenic differentiation between iPSC-derived from healthy and OA cartilage is associated with changes in epigenetic regulation and metabolic transcriptomic signatures

Nazir M. Khan, Martha Elena Diaz-Hernandez, Samir Chihab, Priyanka Priyadarshani, Pallavi Bhattaram, Luke J. Mortensen, Rosa M Guzzo, Hicham Drissi

bioRxiv 2022.10.14.512213; doi: https://doi.org/10.1101/2022.10.14.512213

Share This Article:

Citation Tools

Differential chondrogenic differentiation between iPSC-derived from healthy and OA cartilage is associated with changes in epigenetic regulation and metabolic transcriptomic signatures

Nazir M. Khan, Martha Elena Diaz-Hernandez, Samir Chihab, Priyanka Priyadarshani, Pallavi Bhattaram, Luke J. Mortensen, Rosa M Guzzo, Hicham Drissi

bioRxiv 2022.10.14.512213; doi: https://doi.org/10.1101/2022.10.14.512213

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Cell Biology

Subject Areas

All Articles

Animal Behavior and Cognition (4691)
Biochemistry (10381)
Bioengineering (7698)
Bioinformatics (26381)
Biophysics (13553)
Cancer Biology (10735)
Cell Biology (15465)
Clinical Trials (138)
Developmental Biology (8509)
Ecology (12844)
Epidemiology (2067)
Evolutionary Biology (16890)
Genetics (11417)
Genomics (15499)
Immunology (10643)
Microbiology (25261)
Molecular Biology (10241)
Neuroscience (54610)
Paleontology (402)
Pathology (1671)
Pharmacology and Toxicology (2900)
Physiology (4356)
Plant Biology (9265)
Scientific Communication and Education (1588)
Synthetic Biology (2562)
Systems Biology (6789)
Zoology (1472)