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Canonical and Non-Canonical Psychedelic Drugs Induce Common Network Changes in Human Cortex

Rui Dai, Tony E. Larkin, Zirui Huang, Vijay Tarnal, Paul Picton, Phillip E. Vlisides, Ellen Janke, Amy McKinney, Anthony G. Hudetz, Richard E. Harris, George A. Mashour
doi: https://doi.org/10.1101/2022.10.14.512285
Rui Dai
1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
2Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109
3Michigan Psychedelic Center, University of Michigan Medical School, Ann Arbor, MI, 48109
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Tony E. Larkin
1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
4Chronic Pain and Fatigue Research Center, University of Michigan Medical School, Ann Arbor, MI, 48109
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Zirui Huang
1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
2Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109
3Michigan Psychedelic Center, University of Michigan Medical School, Ann Arbor, MI, 48109
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Vijay Tarnal
1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
2Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109
3Michigan Psychedelic Center, University of Michigan Medical School, Ann Arbor, MI, 48109
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Paul Picton
1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
2Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109
3Michigan Psychedelic Center, University of Michigan Medical School, Ann Arbor, MI, 48109
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Phillip E. Vlisides
1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
2Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109
3Michigan Psychedelic Center, University of Michigan Medical School, Ann Arbor, MI, 48109
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Ellen Janke
1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
2Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109
3Michigan Psychedelic Center, University of Michigan Medical School, Ann Arbor, MI, 48109
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Amy McKinney
1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
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Anthony G. Hudetz
1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
2Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109
3Michigan Psychedelic Center, University of Michigan Medical School, Ann Arbor, MI, 48109
5Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109
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Richard E. Harris
1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
3Michigan Psychedelic Center, University of Michigan Medical School, Ann Arbor, MI, 48109
4Chronic Pain and Fatigue Research Center, University of Michigan Medical School, Ann Arbor, MI, 48109
5Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109
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  • For correspondence: reharris@med.umich.edu gmashour@med.umich.edu
George A. Mashour
1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
2Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109
3Michigan Psychedelic Center, University of Michigan Medical School, Ann Arbor, MI, 48109
5Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109
6Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, 48109
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  • For correspondence: reharris@med.umich.edu gmashour@med.umich.edu
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Article Information

doi 
https://doi.org/10.1101/2022.10.14.512285
History 
  • October 18, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Rui Dai1,2,3,#,
  2. Tony E. Larkin1,4,#,
  3. Zirui Huang1,2,3,
  4. Vijay Tarnal1,2,3,
  5. Paul Picton1,2,3,
  6. Phillip E. Vlisides1,2,3,
  7. Ellen Janke1,2,3,
  8. Amy McKinney1,
  9. Anthony G. Hudetz1,2,3,5,
  10. Richard E. Harris1,3,4,5,* and
  11. George A. Mashour1,2,3,5,6,*
  1. 1Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109
  2. 2Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109
  3. 3Michigan Psychedelic Center, University of Michigan Medical School, Ann Arbor, MI, 48109
  4. 4Chronic Pain and Fatigue Research Center, University of Michigan Medical School, Ann Arbor, MI, 48109
  5. 5Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109
  6. 6Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, 48109
  1. ↵*To whom correspondence should be addressed: Department of Anesthesiology, 1301 Catherine Street, 4102 Medical-Science Building 1, Ann Arbor, MI, 48109, reharris{at}med.umich.edu and gmashour{at}med.umich.edu
  1. ↵# These authors contributed equally to this manuscript.

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Canonical and Non-Canonical Psychedelic Drugs Induce Common Network Changes in Human Cortex
Rui Dai, Tony E. Larkin, Zirui Huang, Vijay Tarnal, Paul Picton, Phillip E. Vlisides, Ellen Janke, Amy McKinney, Anthony G. Hudetz, Richard E. Harris, George A. Mashour
bioRxiv 2022.10.14.512285; doi: https://doi.org/10.1101/2022.10.14.512285
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Canonical and Non-Canonical Psychedelic Drugs Induce Common Network Changes in Human Cortex
Rui Dai, Tony E. Larkin, Zirui Huang, Vijay Tarnal, Paul Picton, Phillip E. Vlisides, Ellen Janke, Amy McKinney, Anthony G. Hudetz, Richard E. Harris, George A. Mashour
bioRxiv 2022.10.14.512285; doi: https://doi.org/10.1101/2022.10.14.512285

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