Nucleotide binding is the critical regulator of ABCG2 conformational transitions

Zsuzsanna Gyöngy; Gábor Mocsár; Éva Hegedűs; Thomas Stockner; Zsuzsanna Ritter; László Homolya; Anita Schamberger; Tamás I. Orbán; Judit Remenyik; Gergely Szakács; Katalin Goda

doi:10.1101/2022.10.19.512890

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Nucleotide binding is the critical regulator of ABCG2 conformational transitions

Zsuzsanna Gyöngy, Gábor Mocsár, Éva Hegedűs, View ORCID ProfileThomas Stockner, Zsuzsanna Ritter, László Homolya, Anita Schamberger, Tamás I. Orbán, Judit Remenyik, View ORCID ProfileGergely Szakács, View ORCID ProfileKatalin Goda

doi: https://doi.org/10.1101/2022.10.19.512890

Zsuzsanna Gyöngy

1Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032, Debrecen, Hungary

2Doctoral School of Molecular Cell and Immune Biology, University of Debrecen, 4032 Debrecen, Hungary

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Gábor Mocsár

1Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032, Debrecen, Hungary

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Éva Hegedűs

1Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032, Debrecen, Hungary

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Thomas Stockner

3Institute of Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria

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ORCID record for Thomas Stockner

Zsuzsanna Ritter

1Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032, Debrecen, Hungary

2Doctoral School of Molecular Cell and Immune Biology, University of Debrecen, 4032 Debrecen, Hungary

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László Homolya

4Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary

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Anita Schamberger

4Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary

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Tamás I. Orbán

4Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary

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Judit Remenyik

5Institute of Food Technology, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, 4032, Debrecen, Hungary

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Gergely Szakács

4Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary

6Institute of Cancer Research, Medical University of Vienna, Vienna, Austria

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ORCID record for Gergely Szakács

Katalin Goda

1Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032, Debrecen, Hungary

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ORCID record for Katalin Goda
For correspondence: goda@med.unideb.hu

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Posted October 21, 2022.

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Nucleotide binding is the critical regulator of ABCG2 conformational transitions

Zsuzsanna Gyöngy, Gábor Mocsár, Éva Hegedűs, Thomas Stockner, Zsuzsanna Ritter, László Homolya, Anita Schamberger, Tamás I. Orbán, Judit Remenyik, Gergely Szakács, Katalin Goda

bioRxiv 2022.10.19.512890; doi: https://doi.org/10.1101/2022.10.19.512890

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Nucleotide binding is the critical regulator of ABCG2 conformational transitions

Zsuzsanna Gyöngy, Gábor Mocsár, Éva Hegedűs, Thomas Stockner, Zsuzsanna Ritter, László Homolya, Anita Schamberger, Tamás I. Orbán, Judit Remenyik, Gergely Szakács, Katalin Goda

bioRxiv 2022.10.19.512890; doi: https://doi.org/10.1101/2022.10.19.512890

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