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Tumor-educated Gr1+CD11b+ cells instigate breast cancer metastasis by twisting cancer cells plasticity via OSM/IL6–JAK signaling

Sanam Peyvandi, Manon Bulliard, Annamaria Kauzlaric, Oriana Coquoz, Yu-Ting Huang, Nathalie Duffey, Laetitia Gafner, Girieca Lorusso, Nadine Fournier, View ORCID ProfileQiang Lan, Curzio Rüegg
doi: https://doi.org/10.1101/2022.10.26.513889
Sanam Peyvandi
1Pathology Unit, Department of Oncology, Microbiology and Immunology (OMI), Faculty of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland
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Manon Bulliard
1Pathology Unit, Department of Oncology, Microbiology and Immunology (OMI), Faculty of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland
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Annamaria Kauzlaric
2Translational Data Science Group, Swiss Institute of Bioinformatics, Lausanne, Switzerland
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Oriana Coquoz
1Pathology Unit, Department of Oncology, Microbiology and Immunology (OMI), Faculty of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland
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Yu-Ting Huang
1Pathology Unit, Department of Oncology, Microbiology and Immunology (OMI), Faculty of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland
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Nathalie Duffey
1Pathology Unit, Department of Oncology, Microbiology and Immunology (OMI), Faculty of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland
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Laetitia Gafner
1Pathology Unit, Department of Oncology, Microbiology and Immunology (OMI), Faculty of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland
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Girieca Lorusso
1Pathology Unit, Department of Oncology, Microbiology and Immunology (OMI), Faculty of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland
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Nadine Fournier
2Translational Data Science Group, Swiss Institute of Bioinformatics, Lausanne, Switzerland
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Qiang Lan
1Pathology Unit, Department of Oncology, Microbiology and Immunology (OMI), Faculty of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland
3Cell and Tissue Dynamics Research Program, Institute of Biotechnology, Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland
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  • ORCID record for Qiang Lan
  • For correspondence: curzio.ruegg@unifr.ch qiang.lan@helsinki.fi
Curzio Rüegg
1Pathology Unit, Department of Oncology, Microbiology and Immunology (OMI), Faculty of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland
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  • For correspondence: curzio.ruegg@unifr.ch qiang.lan@helsinki.fi
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Posted November 07, 2022.
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Tumor-educated Gr1+CD11b+ cells instigate breast cancer metastasis by twisting cancer cells plasticity via OSM/IL6–JAK signaling
Sanam Peyvandi, Manon Bulliard, Annamaria Kauzlaric, Oriana Coquoz, Yu-Ting Huang, Nathalie Duffey, Laetitia Gafner, Girieca Lorusso, Nadine Fournier, Qiang Lan, Curzio Rüegg
bioRxiv 2022.10.26.513889; doi: https://doi.org/10.1101/2022.10.26.513889
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Tumor-educated Gr1+CD11b+ cells instigate breast cancer metastasis by twisting cancer cells plasticity via OSM/IL6–JAK signaling
Sanam Peyvandi, Manon Bulliard, Annamaria Kauzlaric, Oriana Coquoz, Yu-Ting Huang, Nathalie Duffey, Laetitia Gafner, Girieca Lorusso, Nadine Fournier, Qiang Lan, Curzio Rüegg
bioRxiv 2022.10.26.513889; doi: https://doi.org/10.1101/2022.10.26.513889

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